AutismKB 2.0

Annotation Detail for NPAT


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Basic Information Top
Gene Symbol:NPAT ( E14,p220 )
Gene Full Name: nuclear protein, ataxia-telangiectasia locus
Band: 11q22.3
Quick LinksEntrez ID:4863; OMIM: 601448; Uniprot ID:NPAT_HUMAN; ENSEMBL ID: ENSG00000149308; HGNC ID: 7896
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
535Phosphoserine.
554Phosphoserine.
775Phosphoserine; by CDK2.
779Phosphoserine; by CDK2.
1100Phosphoserine; by CDK2.
1228N6-acetyllysine.
1270Phosphothreonine; by CDK2.
1350Phosphothreonine; by CDK2.
Location(AA) Modifications Resource
No data
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_002519
  • Location:chr11 107533327-107598506
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
FOXA1 MCF7GSE15244 107597986 107599170 1184 72
LIN9 SGSE7516 107597813 107599242 1429 21
Rb GrowingGSE19898 107598297 107598751 454 18
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ER E2-MCF7GSE14664 107543084 107543127 43 0
ER E2-MCF7GSE14664 107546500 107546546 46 0
H3K4me2 HCT116GSE10453 107597579 107598365 786 0
H3K4me3 colorectalcancer 107597011 107598795 1784 0
H3ac HepG2E 107596098 107598542 2444 0
Oct1 H2O2-HelaGSE14283 107546500 107546541 41 0
Oct1 HelaGSE14283 107535920 107535977 57 0
Oct1 HelaGSE14283 107543094 107543131 37 0
Oct1 HelaGSE14283 107546500 107546533 33 0
RARG MCF7GSE15244 107597883 107598502 619 0
TAF k562GSE8489 107597401 107598466 1065 0
TFAP2C MCF7GSE21234 107575848 107576376 528 0
hScc1 BcellGSE12603 107597986 107598365 379 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-let-7a hsa-let-7a-1 9 18614752
hsa-let-7a hsa-let-7a-2 11 18614752
hsa-let-7a hsa-let-7a-3 22 18614752
hsa-let-7a* hsa-let-7a-1 9 18614752
hsa-let-7a* hsa-let-7a-3 22 18614752
hsa-let-7b hsa-let-7b 22 18614752
hsa-let-7b* hsa-let-7b 22 18614752
hsa-let-7c hsa-let-7c 21 18614752
hsa-let-7c* hsa-let-7c 21 18614752
hsa-let-7d hsa-let-7d 9 18614752
hsa-let-7d* hsa-let-7d 9 18614752
hsa-let-7e hsa-let-7e 19 18614752
hsa-let-7e* hsa-let-7e 19 18614752
hsa-let-7f hsa-let-7f-1 9 18614752
hsa-let-7f hsa-let-7f-2 X 18614752
hsa-let-7f-1* hsa-let-7f-1 9 18614752
hsa-let-7f-2* hsa-let-7f-2 X 18614752
hsa-let-7g hsa-let-7g 3 18614752
hsa-let-7g* hsa-let-7g 3 18614752
hsa-let-7i hsa-let-7i 12 18614752
hsa-let-7i* hsa-let-7i 12 18614752
hsa-miR-124 hsa-mir-124-1 8 18997113
hsa-miR-124 hsa-mir-124-2 8 18997113
hsa-miR-124 hsa-mir-124-3 20 18997113
hsa-miR-124 hsa-mir-124-1 8 17462994
hsa-miR-124 hsa-mir-124-2 8 17462994
hsa-miR-124 hsa-mir-124-3 20 17462994
hsa-miR-140-3p hsa-mir-140 16 16828749
hsa-miR-140-5p hsa-mir-140 16 16828749
hsa-miR-17 hsa-mir-17 13 19734348
hsa-miR-17* hsa-mir-17 13 19734348
hsa-miR-375 hsa-mir-375 2 19734348
hsa-miR-9 hsa-mir-9-1 1 18997113
hsa-miR-9 hsa-mir-9-2 5 18997113
hsa-miR-9 hsa-mir-9-3 15 18997113
hsa-miR-93 hsa-mir-93 7 19734348
hsa-miR-93* hsa-mir-93 7 19734348
No data
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
5153 mRNA ATM chr11 107598420 107663651 71 mRNA NPAT chr11 107533329 107598507Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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