Annotation Detail for ATP2A2

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Basic Information Top

Gene Symbol:	ATP2A2 ( ATP2B,DAR,DD,DKFZp686P0211,FLJ20293,FLJ38063,MGC45367,SERCA2 )
Gene Full Name:	ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
Band:	12q24.11
Quick Links	Entrez ID:488; OMIM: 108740; Uniprot ID:AT2A2_HUMAN; ENSEMBL ID: ENSG00000174437; HGNC ID: 812
Relate to Another Database:	SFARIGene; denovo-db

Post Translation Modification

Location(AA)	Modification
294	Nitrated tyrosine.
295	Nitrated tyrosine.
464	N6-acetyllysine.
537	Phosphothreonine (By similarity).
663	Phosphoserine.

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CTCF	CD4	GSE12889	109277351	109277548	197	4172
CTCF	CD4	SISSRdata	109277351	109277548	197	4172
Gata2	K562	GSE18868	109276179	109276886	707	3255

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CTCF	G2	GSE9613	109270961	109271419	458	0

Validated miRNA targets

Micro RNA Name	Stem Loop Name	The chromosome that miRNA located	Publication
hsa-let-7b	hsa-let-7b	22	18668040
hsa-let-7b*	hsa-let-7b	22	18668040
hsa-miR-1	hsa-mir-1-2	18	18668040
hsa-miR-1	hsa-mir-1-1	20	18668040
hsa-miR-155	hsa-mir-155	21	18668040
hsa-miR-155*	hsa-mir-155	21	18668040
hsa-miR-16	hsa-mir-16-1	13	18668040
hsa-miR-16	hsa-mir-16-2	3	18668040
hsa-miR-200b	hsa-mir-200b	1	20498046
hsa-miR-200b*	hsa-mir-200b	1	20498046
hsa-miR-214	hsa-mir-214	1	20498046
hsa-miR-214*	hsa-mir-214	1	20498046
hsa-miR-30a	hsa-mir-30a	6	18668040
hsa-miR-30a*	hsa-mir-30a	6	18668040
hsa-miR-30b	hsa-mir-30b	8	18668040
hsa-miR-30b*	hsa-mir-30b	8	18668040
hsa-miR-30c	hsa-mir-30c-2	6	18668040
hsa-miR-30c	hsa-mir-30c-1	1	18668040
hsa-miR-30c-1*	hsa-mir-30c-1	1	18668040
hsa-miR-30c-2*	hsa-mir-30c-2	6	18668040
hsa-miR-30d	hsa-mir-30d	8	18668040
hsa-miR-30d*	hsa-mir-30d	8	18668040
hsa-miR-30e	hsa-mir-30e	1	18668040
hsa-miR-30e*	hsa-mir-30e	1	18668040

ID in Tarbase	Data Type	Support Type	miRNA	Gene	Direct Support	Publication
1219	Unknown	pSILAC	miR-30	ATP2A2	down 50-25%	18668040
Ensembl	Protein Type	Differentially expressed in	Pathology or Event	Mis Regulation	Gene Expression	Tumour Involvement
ENSG00000174437		n_a	n_a	n_a	"epithelium, squamous cell, lymphoblast, lymphocyte, muscle cell, leukocyte"	"benign tumour, malignant tumour, carcinoma, leukaemia, sarcoma"

Cis-Nats regulation

Simple Query:

Paper Collected: 6/30/2018

Last Update: 8/26/2018