AutismKB 2.0

Annotation Detail for NPTX2


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Basic Information Top
Gene Symbol:NPTX2 ( NARP,NP-II,NP2 )
Gene Full Name: neuronal pentraxin II
Band: 7q22.1
Quick LinksEntrez ID:4885; OMIM: 600750; Uniprot ID:NPTX2_HUMAN; ENSEMBL ID: ENSG00000106236; HGNC ID: 7953
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
148N-linked (GlcNAc...) (Potential).
189N-linked (GlcNAc...) (Potential).
393N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
148N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
189N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
393N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
133Phosphothreonine(PKC)HMM predict
140Phosphoserine(CK1)HMM predict
148N-linkedHMM predict
151N-linkedHMM predict
185Phosphoserine(CK1)HMM predict
189N-linkedHMM predict
192Phosphoserine(CK1)HMM predict
217Phosphoserine(PKB)HMM predict
261Phosphoserine(CDC2)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_002523
  • Location:chr7 98084544-98097113
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 98083980 98085067 1087 21
NRSF JurkatGSE13047 98080483 98081829 1346 3389
NRSF mAbJurkat 98075556 98078355 2799 7589
NRSF mAbJurkat 98078858 98079297 439 5467
NRSF mAbJurkat 98079605 98081820 2215 3832
NRSF mAbJurkat 98082298 98083653 1355 1569
NRSF-mono JurkatQuESTdata 98080742 98081802 1060 3273
NRSF pAbJurkat 98078858 98079297 439 5467
NRSF pAbJurkat 98079856 98080294 438 4470
NRSF pAbJurkat 98080906 98081765 859 3209
NRSF pAbJurkat 98082298 98082511 213 2140
NRSF-poly JurkatQuESTdata 98080591 98081829 1238 3335
Oct1 HelaGSE14283 98065644 98065702 58 18872
Oct1 HelaGSE14283 98065724 98065773 49 18796
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 98106325 98106566 241 9332
CTCF G2GSE9613 98109041 98109486 445 12150
CTCF G2GSE9613 98113395 98113582 187 16375
Nanog hESGSE18292 98097415 98097667 252 428
Oct1 HelaGSE14283 98101930 98101967 37 4835
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 98086875 98087405 530 0
H3K27me3 colorectalcancer 98085878 98086559 681 0
Oct4 hESGSE17917 98085822 98086261 439 0
hScc1 BcellGSE12603 98084284 98084810 526 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018