AutismKB 2.0

Annotation Detail for SLC11A2


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Basic Information Top
Gene Symbol:SLC11A2 ( DCT1,DMT1,FLJ37416,NRAMP2 )
Gene Full Name: solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
Band: 12q13.12
Quick LinksEntrez ID:4891; OMIM: 600523; Uniprot ID:NRAM2_HUMAN; ENSEMBL ID: ENSG00000110911; HGNC ID: 10908
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
21Phosphoserine (By similarity).
336N-linked (GlcNAc...) (Potential).
349N-linked (GlcNAc...) (Potential).
564Phosphoserine (By similarity).
567Phosphoserine (By similarity).
Location(AA) Modifications Resource
336N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
349N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
13Phosphoserine(IKK)HMM predict
33N-linkedHMM predict
35O-linkedHMM predict
37Phosphoserine(ATM)HMM predict
39Phosphoserine(IKK)HMM predict
39Phosphoserine(CDC2)HMM predict
39Phosphoserine(ATM)HMM predict
46Phosphotyrosine(Syk)HMM predict
46SulfotyrosineHMM predict
234Phosphoserine(ATM)HMM predict
270Phosphotyrosine(Jak)HMM predict
336N-linkedHMM predict
349N-linkedHMM predict
386O-linkedHMM predict
387O-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_000617
  • Location:chr12 49666043-49706408
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 49708110 49709240 1130 2267
ER Fulvestrant-MCF7GSE14664 49713532 49713567 35 7141
FOXA1 MCF7GSE15244 49707401 49707720 319 1152
Fos K562GSE19551 49706059 49706834 775 38
H3ac HepG2E 49707401 49708218 817 1401
HIF1 HypoHepG2 49716177 49716850 673 10105
RARA MCF7GSE15244 49707830 49709495 1665 2254
RARG MCF7GSE15244 49707401 49709495 2094 2040
TFAP2C MCF7GSE21234 49706091 49706934 843 104
TFAP2C MCF7GSE21234 49708105 49709706 1601 2497
hScc1 CdLSGSE12603 49708147 49708623 476 1977
hScc1 G2GSE9613 49708075 49708521 446 1890
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 49667105 49667339 234 0
CTCF CD4SISSRdata 49667105 49667339 234 0
CTCF G2GSE9613 49666909 49667535 626 0
CTCF G2GSE9613 49684696 49684838 142 0
CTCF G2GSE9613 49705854 49706710 856 0
ER E2-MCF7GSE14664 49684520 49684556 36 0
ER MCF7GSE19013 49705574 49706696 1122 0
FOXA1 DLD1GSE12801 49704740 49705317 577 0
FOXA1 MCF7GSE15244 49667279 49667535 256 0
FOXA1 MCF7GSE15244 49685578 49685804 226 0
FOXA1 MCF7GSE15244 49704740 49706113 1373 0
FoxA1 MCF7MACSdata 49704940 49705111 171 0
GATA3 MCF7GSE15244 49685542 49685804 262 0
H3K4me2 HCT116GSE10453 49704740 49705712 972 0
H3K4me3 colorectalcancer 49704844 49705961 1117 0
H3ac HepG2E 49704740 49705961 1221 0
NRSF pAbJurkat 49706222 49706524 302 0
Nanog hESGSE18292 49689222 49689831 609 0
RARA MCF7GSE15244 49666806 49667535 729 0
RARA MCF7GSE15244 49684438 49684802 364 0
RARA MCF7GSE15244 49685353 49685804 451 0
RARA MCF7GSE15244 49704125 49704415 290 0
RARA MCF7GSE15244 49704740 49705961 1221 0
RARG MCF7GSE15244 49672821 49673214 393 0
RARG MCF7GSE15244 49685353 49685804 451 0
RARG MCF7GSE15244 49704740 49705923 1183 0
Rb GrowingGSE19898 49704824 49705102 278 0
TAF HelaGSE8489 49704125 49704415 290 0
TAF HelaGSE8489 49704740 49705961 1221 0
TAF k562GSE8489 49704740 49705961 1221 0
TAFII hESGSE17917 49667068 49667314 246 0
hScc1 BcellGSE12603 49666946 49667535 589 0
hScc1 BcellGSE12603 49705645 49706772 1127 0
hScc1 CdLSGSE12603 49666878 49667457 579 0
hScc1 CdLSGSE12603 49705854 49706555 701 0
hScc1 G2GSE9613 49666735 49667457 722 0
hScc1 G2GSE9613 49705888 49706674 786 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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