AutismKB 2.0

Annotation Detail for NTHL1


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Basic Information Top
Gene Symbol:NTHL1 ( NTH1,OCTS3 )
Gene Full Name: nth endonuclease III-like 1 (E. coli)
Band: 16p13.3
Quick LinksEntrez ID:4913; OMIM: 602656; Uniprot ID:NTHL1_HUMAN; ENSEMBL ID: ENSG00000065057; HGNC ID: 8028
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
18Phosphothreonine(PKC)HMM predict
22PhosphoserineHMM predict
22Phosphoserine(PKG)HMM predict
51Phosphoserine(PKG)HMM predict
53PhosphoserineHMM predict
53Phosphoserine(CDC2)HMM predict
73O-linkedHMM predict
75O-linkedHMM predict
140Phosphoserine(ATM)HMM predict
160Phosphothreonine(PKC)HMM predict
258Phosphoserine(IKK)HMM predict
297CysteineHMM predict
306CysteineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_002528
  • Location:chr16 2029816-2037867
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
VDR GM10861-UnstimGSE22484 2037242 2038586 1344 47
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
FoxA1 MCF7MACSdata 2029577 2030007 430 25
TFAP2C MCF7GSE21234 2029067 2029959 892 304
p130 QuiescentGSE19898 2029588 2029824 236 111
p130 shRbQuiescentGSE19898 2028944 2029394 450 648
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 2029764 2030093 329 0
CTCF G2GSE9613 2032239 2032416 177 0
CTCF G2GSE9613 2033928 2034575 647 0
CTCF G2GSE9613 2037345 2037954 609 0
FOXA1 MCF7GSE15244 2029356 2030523 1167 0
NFkBII GM12892GSE19485 2033540 2034587 1047 0
NRSF pAbJurkat 2034206 2034616 410 0
P300 T0-glioblastomaGSE21026 2037518 2038205 687 0
P300 T30-glioblastomaGSE21026 2037129 2038361 1232 0
TFAP2C MCF7GSE21234 2033273 2033922 649 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
9472 EST chr16 2037466 2038682 158 mRNA NTHL1 chr16 2029816 2037868Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018