AutismKB 2.0

Annotation Detail for NTRK2


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:NTRK2 ( GP145-TrkB,TRKB )
Gene Full Name: neurotrophic tyrosine kinase, receptor, type 2
Band: 9q21.33
Quick LinksEntrez ID:4915; OMIM: 600456; Uniprot ID:NTRK2_HUMAN; ENSEMBL ID: ENSG00000148053; HGNC ID: 8032
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
67N-linked (GlcNAc...).
95N-linked (GlcNAc...) (Potential).
121N-linked (GlcNAc...).
178N-linked (GlcNAc...) (Potential).
205N-linked (GlcNAc...) (Potential).
241N-linked (GlcNAc...) (Potential).
254N-linked (GlcNAc...).
280N-linked (GlcNAc...) (Potential).
325N-linked (GlcNAc...) (Potential).
338N-linked (GlcNAc...) (Potential).
412N-linked (GlcNAc...) (Potential).
516Phosphotyrosine; by autocatalysis (By
702Phosphotyrosine; by autocatalysis (By
706Phosphotyrosine; by autocatalysis (By
707Phosphotyrosine; by autocatalysis (By
817Phosphotyrosine; by autocatalysis (By
Location(AA) Modifications Resource
67N-linked (GlcNAc...).Swiss-Prot 53.0
95N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
121N-linked (GlcNAc...).Swiss-Prot 53.0
178N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
205N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
241N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
254N-linked (GlcNAc...).Swiss-Prot 53.0
280N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
325N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
338N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
412N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
516Phosphotyrosine (by autocatalysis) (Bysimilarity).Swiss-Prot 53.0
702Phosphotyrosine (by autocatalysis) (Bysimilarity).Swiss-Prot 53.0
706Phosphotyrosine (by autocatalysis) (Bysimilarity).Swiss-Prot 53.0
707Phosphotyrosine (by autocatalysis) (Bysimilarity).Swiss-Prot 53.0
817Phosphotyrosine (by autocatalysis) (Bysimilarity).Swiss-Prot 53.0
Location(AA) Modification Resource
34O-linkedHMM predict
35O-linkedHMM predict
67N-linkedHMM predict
95N-linkedHMM predict
121N-linkedHMM predict
125N-linkedHMM predict
168Phosphoserine(IKK)HMM predict
178N-linkedHMM predict
183N-linkedHMM predict
205N-linkedHMM predict
241N-linkedHMM predict
254N-linkedHMM predict
260Phosphoserine(CK1)HMM predict
278Phosphoserine(IKK)HMM predict
280N-linkedHMM predict
282O-linkedHMM predict
297Phosphoserine(CK1)HMM predict
325N-linkedHMM predict
338N-linkedHMM predict
350N-linkedHMM predict
355N-linkedHMM predict
356N-linkedHMM predict
359Phosphotyrosine(INSR)HMM predict
392SulfotyrosineHMM predict
397Phosphotyrosine(Syk)HMM predict
397SulfotyrosineHMM predict
472Phosphoserine(CK2)HMM predict
486N-linkedHMM predict
489N-linkedHMM predict
490Phosphothreonine(MAPK)HMM predict
492O-linkedHMM predict
492Phosphoserine(CK1)HMM predict
494O-linkedHMM predict
516PhosphotyrosineHMM predict
573Phosphothreonine(PKC)HMM predict
651Phosphoserine(ATM)HMM predict
702PhosphotyrosineHMM predict
706Phosphotyrosine(Syk)HMM predict
706Phosphotyrosine(Jak)HMM predict
706PhosphotyrosineHMM predict
727Phosphotyrosine(EGFR)HMM predict
731Phosphothreonine(PKA)HMM predict
783Phosphotyrosine(Syk)HMM predict
783PhosphotyrosineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001007097
  • Location:chr9 86474445-86620440
  • strand:+
No data
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 86502350 86502594 244 0
CTCF CD4SISSRdata 86502350 86502594 244 0
ER E2-MCF7GSE14664 86489200 86489232 32 0
ER E2-MCF7GSE14664 86496461 86496493 32 0
ER E2-MCF7GSE14664 86544244 86544292 48 0
ER Fulvestrant-MCF7GSE14664 86544243 86544293 50 0
ER MCF7GSE19013 86593959 86594697 738 0
FOXA1 MCF7GSE15244 86593944 86594717 773 0
H3K27me3 colorectalcancer 86476376 86476805 429 0
H3K4me3 colorectalcancer 86475137 86475429 292 0
NFkBII GM10847GSE19485 86563519 86564838 1319 0
NFkBII GM12878GSE19485 86563404 86567435 4031 0
NFkBII GM12892GSE19485 86563523 86564879 1356 0
NFkBII GM15510GSE19485 86563455 86565058 1603 0
NFkBII GM18505GSE19485 86563545 86565308 1763 0
NFkBII GM18526GSE19485 86563501 86565025 1524 0
Nanog ESGSE20650 86512942 86513701 759 0
Nanog hESGSE18292 86499078 86499409 331 0
Nanog hESGSE18292 86512963 86513687 724 0
Oct1 HelaGSE14283 86514752 86514786 34 0
Oct1 HelaGSE14283 86519435 86519469 34 0
Oct1 HelaGSE14283 86544196 86544294 98 0
Oct1 HelaGSE14283 86576065 86576096 31 0
Oct1 HelaGSE14283 86581727 86581768 41 0
Oct1 HelaGSE14283 86594238 86594278 40 0
Oct4 hESGSE21916 86513144 86513605 461 0
Oct4 hESGSE21916 86574213 86574574 361 0
RARA MCF7GSE15244 86593654 86594906 1252 0
TFAP2C MCF7GSE21234 86502022 86502644 622 0
TFAP2C MCF7GSE21234 86516490 86517097 607 0
TFAP2C MCF7GSE21234 86612770 86613658 888 0
hScc1 BcellGSE12603 86474603 86474918 315 0
hScc1 BcellGSE12603 86502247 86502890 643 0
hScc1 CdLSGSE12603 86501852 86502614 762 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-200c hsa-mir-200c 12 19435871
hsa-miR-200c* hsa-mir-200c 12 19435871
No data
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
26654 mRNA NTRK2 chr9 84514179 84660175 12452 EST chr9 84638668 84651120 Non-exonic Bidirectional (NOB) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved