AutismKB 2.0

Annotation Detail for ROR2


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Basic Information Top
Gene Symbol:ROR2 ( BDB,BDB1,MGC163394,NTRKR2 )
Gene Full Name: receptor tyrosine kinase-like orphan receptor 2
Band: 9q22.31
Quick LinksEntrez ID:4920; OMIM: 602337; Uniprot ID:ROR2_HUMAN; ENSEMBL ID: ENSG00000169071; HGNC ID: 10257
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
70N-linked (GlcNAc...) (Potential).
188N-linked (GlcNAc...) (Potential).
318N-linked (GlcNAc...) (Potential).
449Phosphoserine.
469Sulfoserine; partial.
471Sulfoserine; partial.
646Phosphotyrosine; by autocatalysis (By
Location(AA) Modifications Resource
70N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
188N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
318N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
469Sulfoserine; partial.Swiss-Prot 53.0
471Sulfoserine; partial.Swiss-Prot 53.0
646Phosphotyrosine; by autocatalysis (Bysimilarity).Swiss-Prot 53.0
Location(AA) Modification Resource
32Phosphoserine(CK2)HMM predict
56Phosphothreonine(PKC)HMM predict
70N-linkedHMM predict
159Phosphoserine(ATM)HMM predict
168SulfotyrosineHMM predict
188N-linkedHMM predict
224Phosphoserine(ATM)HMM predict
239S-palmitoylHMM predict
245Phosphothreonine(CDK)HMM predict
245Phosphothreonine(MAPK)HMM predict
318N-linkedHMM predict
426S-palmitoylHMM predict
428S-palmitoylHMM predict
435Phosphoserine(PKG)HMM predict
435Phosphoserine(IKK)HMM predict
438Phosphothreonine(CDC2)HMM predict
438Phosphothreonine(CDK)HMM predict
438Phosphothreonine(MAPK)HMM predict
447Phosphoserine(ATM)HMM predict
449Phosphoserine(ATM)HMM predict
508Phosphothreonine(PKC)HMM predict
576Phosphoserine(CK2)HMM predict
645Phosphotyrosine(Jak)HMM predict
696Phosphotyrosine(Syk)HMM predict
751N-linkedHMM predict
754N-linkedHMM predict
756N-linkedHMM predict
761Phosphothreonine(PKC)HMM predict
762Phosphoserine(IKK)HMM predict
762O-linkedHMM predict
762O-linkedHMM predict
762O-linkedHMM predict
766N-linkedHMM predict
768O-linkedHMM predict
768O-linkedHMM predict
771O-linkedHMM predict
772Phosphoserine(IKK)HMM predict
772O-linkedHMM predict
772O-linkedHMM predict
775O-linkedHMM predict
776PhosphoserineHMM predict
776Phosphoserine(CDC2)HMM predict
776Phosphoserine(IKK)HMM predict
776Phosphoserine(CDK)HMM predict
776Phosphoserine(MAPK)HMM predict
779Phosphoserine(IKK)HMM predict
780N-linkedHMM predict
783N-linkedHMM predict
786Phosphotyrosine(Jak)HMM predict
824Phosphotyrosine(Syk)HMM predict
864Phosphoserine(IKK)HMM predict
866O-linkedHMM predict
866Phosphoserine(CK1)HMM predict
869O-linkedHMM predict
870O-linkedHMM predict
873Phosphotyrosine(Jak)HMM predict
875O-linkedHMM predict
876O-linkedHMM predict
879O-linkedHMM predict
881O-linkedHMM predict
919Phosphoserine(CK1)HMM predict
919Phosphoserine(CK2)HMM predict
919Phosphoserine(IKK)HMM predict
919Phosphoserine(ATM)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_004560
  • Location:chr9 93524704-93752264
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 93752347 93752488 141 153
CTCF CD4GSE12889 93756944 93757072 128 4744
CTCF CD4SISSRdata 93752347 93752488 141 153
CTCF CD4SISSRdata 93756944 93757072 128 4744
Myc K562GSE19551 93756800 93757324 524 4798
Nanog hESGSE18292 93756934 93757125 191 4765
Oct1 H2O2-HelaGSE14283 93767031 93767057 26 14780
hScc1 BcellGSE12603 93752124 93752616 492 106
p63 keratinocytesGSE17611 93765680 93766502 822 13827
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
FOXA1 MCF7GSE15244 93512220 93512880 660 12155
Rb shRbQuiescentGSE19898 93509099 93509232 133 15539
TAF HelaGSE8489 93512454 93512880 426 12038
TAF k562GSE8489 93512147 93512880 733 12191
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 93529499 93529647 148 0
CTCF CD4GSE12889 93536552 93536860 308 0
CTCF CD4GSE12889 93577554 93577835 281 0
CTCF CD4SISSRdata 93529499 93529647 148 0
CTCF CD4SISSRdata 93536552 93536860 308 0
CTCF CD4SISSRdata 93577554 93577835 281 0
CTCF HelaGSE12889 93536489 93536838 349 0
CTCF JurkatGSE12889 93536479 93536832 353 0
CTCF JurkatGSE12889 93577596 93577812 216 0
ER Fulvestrant-MCF7GSE14664 93620051 93620089 38 0
FOXA1 MCF7GSE15244 93598684 93601826 3142 0
Fos K562GSE19551 93716595 93717148 553 0
GABP k562GSE8489 93707810 93708190 380 0
Gata2 K562GSE18868 93701761 93702714 953 0
Nanog ESGSE20650 93741945 93742510 565 0
Nanog hESGSE18292 93583096 93583276 180 0
Nanog hESGSE18292 93688735 93689205 470 0
Nanog hESGSE18292 93710530 93710738 208 0
Nanog hESGSE18292 93742310 93742679 369 0
Oct1 H2O2-HelaGSE14283 93688123 93688153 30 0
Oct1 HelaGSE14283 93593372 93593432 60 0
Oct1 HelaGSE14283 93620052 93620086 34 0
Oct4 hESGSE17917 93529527 93529786 259 0
Rb GrowingGSE19898 93699062 93699287 225 0
STAT1 HeLaGSE12783 93689328 93690045 717 0
STAT1 IFNSISSRdata 93688999 93689938 939 0
Stat6 IL-4-hr1GSE17850 93600902 93601552 650 0
TAF k562GSE8489 93707810 93708538 728 0
TAF k562GSE8489 93747404 93748259 855 0
TAF k562GSE8489 93748568 93749270 702 0
TAF k562GSE8489 93749764 93750252 488 0
TFAP2C MCF7GSE21234 93577506 93577952 446 0
TFAP2C MCF7GSE21234 93598569 93601646 3077 0
TFAP2C MCF7GSE21234 93611537 93612430 893 0
hScc1 BcellGSE12603 93525638 93525929 291 0
hScc1 BcellGSE12603 93535477 93535803 326 0
hScc1 BcellGSE12603 93536505 93537185 680 0
hScc1 BcellGSE12603 93577402 93577838 436 0
hScc1 BcellGSE12603 93586077 93586427 350 0
hScc1 BcellGSE12603 93620709 93621302 593 0
hScc1 BcellGSE12603 93637926 93638103 177 0
hScc1 BcellGSE12603 93750957 93751338 381 0
hScc1 CdLSGSE12603 93577402 93578096 694 0
hScc1 G2GSE9613 93560427 93560995 568 0
hScc1 G2GSE9613 93577402 93577838 436 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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