AutismKB 2.0

Annotation Detail for NUMA1


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Basic Information Top
Gene Symbol:NUMA1 ( NUMA )
Gene Full Name: nuclear mitotic apparatus protein 1
Band: 11q13.4
Quick LinksEntrez ID:4926; OMIM: 164009; Uniprot ID:NUMA1_HUMAN; ENSEMBL ID: ENSG00000137497; HGNC ID: 8059
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
169Phosphoserine.
172Phosphoserine.
198Phosphoserine.
200Phosphoserine.
203Phosphoserine.
211Phosphothreonine.
271Phosphoserine.
379N6-acetyllysine.
388Phosphoserine.
395Phosphoserine.
820Phosphoserine.
891N6-acetyllysine.
963Phosphothreonine.
1225Phosphoserine.
1262Phosphoserine.
1280Phosphoserine.
1511N6-acetyllysine.
1601Phosphoserine.
1721Phosphoserine.
1724Phosphoserine.
1728Phosphoserine.
1733Phosphothreonine.
1757Phosphoserine.
1760Phosphoserine.
1769Phosphoserine.
1772Phosphoserine.
1774Phosphotyrosine.
1776Phosphothreonine.
1788Phosphoserine.
1789Phosphoserine.
1792Phosphoserine.
1800Phosphoserine.
1804Phosphothreonine.
1830Phosphoserine.
1833Phosphoserine.
1834Phosphoserine.
1836Phosphotyrosine.
1837Phosphoserine.
1840Phosphoserine.
1847Phosphoserine.
1853Phosphoserine.
1862Phosphoserine.
1872Phosphoserine.
1887Phosphoserine.
1945Phosphoserine.
1969Phosphoserine.
1991Phosphoserine.
2000Phosphothreonine.
2055Phosphothreonine.
2074Phosphoserine.
2077Phosphoserine.
2106Phosphothreonine.
Location(AA) Modifications Resource
169Phosphoserine.Swiss-Prot 53.0
169PhosphoserinePhospho.ELM 6.0
172Phosphoserine.Swiss-Prot 53.0
172PhosphoserinePhospho.ELM 6.0
200Phosphoserine.Swiss-Prot 53.0
200PhosphoserinePhospho.ELM 6.0
203Phosphoserine.Swiss-Prot 53.0
203PhosphoserinePhospho.ELM 6.0
211PhosphothreoninePhospho.ELM 6.0
211Phosphothreonine.Swiss-Prot 53.0
1262PhosphoserinePhospho.ELM 6.0
1262Phosphoserine.Swiss-Prot 53.0
1721Phosphoserine.Swiss-Prot 53.0
1721PhosphoserinePhospho.ELM 6.0
1724PhosphoserinePhospho.ELM 6.0
1724Phosphoserine.Swiss-Prot 53.0
1728Phosphoserine.Swiss-Prot 53.0
1733PhosphothreoninePhospho.ELM 6.0
1733Phosphothreonine.Swiss-Prot 53.0
1739PhosphoserinePhospho.ELM 6.0
1757Phosphoserine.Swiss-Prot 53.0
1757PhosphoserinePhospho.ELM 6.0
1769PhosphoserinePhospho.ELM 6.0
1769Phosphoserine.Swiss-Prot 53.0
1772PhosphoserinePhospho.ELM 6.0
1772Phosphoserine.Swiss-Prot 53.0
1774Phosphotyrosine.Swiss-Prot 53.0
1774PhosphotyrosinePhospho.ELM 6.0
1776Phosphothreonine.Swiss-Prot 53.0
1776PhosphothreoninePhospho.ELM 6.0
1830Phosphoserine.Swiss-Prot 53.0
1830PhosphoserinePhospho.ELM 6.0
1833Phosphoserine.Swiss-Prot 53.0
1833PhosphoserinePhospho.ELM 6.0
1834PhosphoserinePhospho.ELM 6.0
1834Phosphoserine.Swiss-Prot 53.0
1837PhosphoserinePhospho.ELM 6.0
1840Phosphoserine.Swiss-Prot 53.0
1847Phosphoserine.Swiss-Prot 53.0
1853PhosphoserinePhospho.ELM 6.0
1853Phosphoserine.Swiss-Prot 53.0
1862PhosphoserinePhospho.ELM 6.0
1862Phosphoserine.Swiss-Prot 53.0
1872Phosphoserine.Swiss-Prot 53.0
1872PhosphoserinePhospho.ELM 6.0
1945Phosphoserine.Swiss-Prot 53.0
1945PhosphoserinePhospho.ELM 6.0
2000Phosphothreonine.Swiss-Prot 53.0
2000PhosphothreoninePhospho.ELM 6.0
2003PhosphoserinePhospho.ELM 6.0
2055Phosphothreonine.Swiss-Prot 53.0
2106Phosphothreonine.Swiss-Prot 53.0
Location(AA) Modification Resource
76Phosphoserine(PKA)HMM predict
109Phosphoserine(CK1)HMM predict
159O-linkedHMM predict
163O-linkedHMM predict
190Phosphoserine(CK1)HMM predict
190Phosphoserine(CDC2)HMM predict
200Phosphoserine(CDC2)HMM predict
200Phosphoserine(ATM)HMM predict
200Phosphoserine(IKK)HMM predict
203Phosphoserine(MAPK)HMM predict
271Phosphoserine(CDC2)HMM predict
271Phosphoserine(IKK)HMM predict
352Phosphothreonine(PKC)HMM predict
388Phosphoserine(PKG)HMM predict
388Phosphoserine(ATM)HMM predict
395Phosphoserine(ATM)HMM predict
428N-linkedHMM predict
429N-linkedHMM predict
476Phosphoserine(CK1)HMM predict
479Phosphoserine(ATM)HMM predict
502O-linkedHMM predict
511N-linkedHMM predict
559Phosphoserine(CK1)HMM predict
633O-linkedHMM predict
633Phosphoserine(PKG)HMM predict
637Phosphoserine(IKK)HMM predict
688Phosphothreonine(PKC)HMM predict
688Phosphothreonine(CK2)HMM predict
745Phosphoserine(CK1)HMM predict
820Phosphoserine(ATM)HMM predict
820PhosphoserineHMM predict
827Phosphotyrosine(SRC)HMM predict
837Phosphothreonine(PKC)HMM predict
903Phosphoserine(CK1)HMM predict
912Phosphothreonine(CK2)HMM predict
921Phosphothreonine(PKC)HMM predict
991Phosphoserine(ATM)HMM predict
1010Phosphothreonine(PKC)HMM predict
1086Phosphothreonine(PKC)HMM predict
1145Phosphoserine(CK1)HMM predict
1149Phosphoserine(CK1)HMM predict
1181Phosphoserine(ATM)HMM predict
1225Phosphoserine(PKG)HMM predict
1229Phosphoserine(CK1)HMM predict
1501Phosphothreonine(PKC)HMM predict
1565Phosphoserine(IKK)HMM predict
1582Phosphoserine(ATM)HMM predict
1601Phosphoserine(ATM)HMM predict
1672Phosphothreonine(PKC)HMM predict
1749O-linkedHMM predict
1757Phosphoserine(MAPK)HMM predict
1760Phosphoserine(ATM)HMM predict
1804Phosphothreonine(PKC)HMM predict
1811Phosphothreonine(PKA)HMM predict
1811Phosphothreonine(PKC)HMM predict
1812Phosphothreonine(PKA)HMM predict
1816N-linkedHMM predict
1830Phosphoserine(IKK)HMM predict
1832N-linkedHMM predict
1837O-linkedHMM predict
1838O-linkedHMM predict
1844O-linkedHMM predict
1844Phosphoserine(ATM)HMM predict
1844Phosphoserine(IKK)HMM predict
1847O-linkedHMM predict
1851O-linkedHMM predict
1852O-linkedHMM predict
1852O-linkedHMM predict
1852Phosphoserine(CK1)HMM predict
1865Phosphotyrosine(INSR)HMM predict
1879Phosphothreonine(PKC)HMM predict
1882Phosphoserine(CDC2)HMM predict
1883Phosphoserine(PKC)HMM predict
1887Phosphoserine(PKG)HMM predict
1887Phosphoserine(IKK)HMM predict
1893O-linkedHMM predict
1945Phosphoserine(CK1)HMM predict
1964Phosphothreonine(PKC)HMM predict
1969Phosphoserine(PKG)HMM predict
1991Phosphoserine(PKA)HMM predict
1991Phosphoserine(PKG)HMM predict
2000Phosphothreonine(CDC2)HMM predict
2000Phosphothreonine(MAPK)HMM predict
2000Phosphothreonine(CDK)HMM predict
2003O-linkedHMM predict
2015Phosphothreonine(MAPK)HMM predict
2015Phosphothreonine(CDK)HMM predict
2026Phosphoserine(PKG)HMM predict
2027Phosphothreonine(PKG)HMM predict
2027Phosphothreonine(PKA)HMM predict
2039O-linkedHMM predict
2047Phosphoserine(PKB)HMM predict
2084Phosphothreonine(PKC)HMM predict
2087Phosphoserine(CDC2)HMM predict
2093O-linkedHMM predict
2094O-linkedHMM predict
2096O-linkedHMM predict
2096O-linkedHMM predict
2099O-linkedHMM predict
2106Phosphothreonine(MAPK)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_006185
  • Location:chr11 71391558-71469220
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
LIN9 G0GSE7516 71468675 71469804 1129 19
p130 QuiescentGSE19898 71469008 71469672 664 120
p130 SenescentGSE19898 71468714 71469919 1205 96
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 71413816 71414185 369 0
CTCF CD4GSE12889 71463937 71464065 128 0
CTCF CD4SISSRdata 71413816 71414185 369 0
CTCF CD4SISSRdata 71463937 71464065 128 0
CTCF HelaGSE12889 71413895 71414075 180 0
E2F4 G0GSE7516 71468607 71469668 1061 0
FOXA1 MCF7GSE15244 71411984 71412370 386 0
FOXA1 MCF7GSE15244 71414135 71414414 279 0
FOXA1 MCF7GSE15244 71428322 71431022 2700 0
FOXA1 MCF7GSE15244 71437366 71437987 621 0
FOXA1 MCF7GSE15244 71468248 71468971 723 0
H3K4me2 HCT116GSE10453 71467230 71467928 698 0
H3K4me2 HCT116GSE10453 71468248 71468923 675 0
H3K4me3 colorectalcancer 71468331 71468923 592 0
H3ac HepG2E 71426957 71429373 2416 0
H3ac HepG2E 71431190 71431486 296 0
H3ac HepG2E 71466883 71467928 1045 0
H3ac HepG2E 71468248 71469017 769 0
KLF4 hESGSE17917 71468959 71469369 410 0
LIN9 SGSE7516 71468367 71469773 1406 0
NRSF pAbJurkat 71397982 71398240 258 0
NRSF pAbJurkat 71402199 71402507 308 0
NRSF pAbJurkat 71404055 71404922 867 0
Nanog hESGSE18292 71437408 71437909 501 0
Oct1 HelaGSE14283 71401546 71401615 69 0
Oct1 HelaGSE14283 71443239 71443273 34 0
RARA MCF7GSE15244 71411865 71413030 1165 0
RARA MCF7GSE15244 71458306 71458868 562 0
RARA MCF7GSE15244 71467350 71467928 578 0
RARA MCF7GSE15244 71468248 71468675 427 0
RARG MCF7GSE15244 71405101 71405643 542 0
RARG MCF7GSE15244 71411679 71413558 1879 0
RARG MCF7GSE15244 71414135 71414486 351 0
RARG MCF7GSE15244 71427558 71428676 1118 0
RARG MCF7GSE15244 71430569 71431022 453 0
RARG MCF7GSE15244 71458128 71458762 634 0
RARG MCF7GSE15244 71467425 71467928 503 0
RARG MCF7GSE15244 71468248 71468743 495 0
Sox2 hESGSE18292 71429594 71429838 244 0
Sox2 hESGSE18292 71437556 71437849 293 0
TAF HelaGSE8489 71467644 71467928 284 0
TAF HelaGSE8489 71468248 71468897 649 0
TAF k562GSE8489 71468248 71468923 675 0
TFAP2C MCF7GSE21234 71428447 71429659 1212 0
hScc1 BcellGSE12603 71402993 71403371 378 0
hScc1 BcellGSE12603 71403712 71405030 1318 0
hScc1 BcellGSE12603 71413920 71414211 291 0
hScc1 BcellGSE12603 71468971 71469437 466 0
hScc1 CdLSGSE12603 71404455 71404810 355 0
hScc1 CdLSGSE12603 71413920 71414593 673 0
hScc1 G2GSE9613 71413920 71414211 291 0
p130 QuiescentGSE19898 71430292 71430984 692 0
p130 shRbQuiescentGSE19898 71429680 71430789 1109 0
p130 G0GSE7516 71468607 71469668 1061 0
p63 keratinocytesGSE17611 71446998 71447977 979 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-192 hsa-mir-192 11 19205878
hsa-miR-192* hsa-mir-192 11 19205878
No data
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
4855 mRNA IL18BP chr11 71387756 71392447 666 mRNA NUMA1 chr11 71391566 71469209Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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