AutismKB 2.0

Annotation Detail for OAS1


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Basic Information Top
Gene Symbol:OAS1 ( IFI-4,OIAS,OIASI )
Gene Full Name: 2',5'-oligoadenylate synthetase 1, 40/46kDa
Band: 12q24.2
Quick LinksEntrez ID:4938; OMIM: 164350; Uniprot ID:OAS1_HUMAN; ENSEMBL ID: ENSG00000089127; HGNC ID: 8086
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
19SulfotyrosineHMM predict
83Phosphoserine(CDC2)HMM predict
133Phosphoserine(IKK)HMM predict
170Phosphotyrosine(EGFR)HMM predict
292Phosphothreonine(PKC)HMM predict
338Phosphoserine(CDC2)HMM predict
351Phosphoserine(CK2)HMM predict
382Phosphothreonine(PKC)HMM predict
388Phosphothreonine(MAPK)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_002534
  • Location:chr12 111829121-111840211
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ER E2-MCF7GSE14664 111825012 111825064 52 4084
Oct1 HelaGSE14283 111825413 111825455 42 3688
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 111829064 111829323 259 0
CTCF CD4SISSRdata 111829064 111829323 259 0
FOXA1 MCF7GSE15244 111829053 111829440 387 0
FOXA1 MCF7GSE15244 111838652 111838953 301 0
P300 T0-glioblastomaGSE21026 111838262 111839008 746 0
P300 T30-glioblastomaGSE21026 111838441 111839089 648 0
Pol2 GM12878GSE19551 111828827 111830034 1207 0
RARA MCF7GSE15244 111828863 111829440 577 0
RARA MCF7GSE15244 111838652 111838976 324 0
RARG MCF7GSE15244 111828863 111829440 577 0
TAF HelaGSE8489 111828863 111829440 577 0
TFAP2C MCF7GSE21234 111838518 111839079 561 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-21 hsa-mir-21 17 18358831
hsa-miR-21* hsa-mir-21 17 18358831
hsa-miR-30a hsa-mir-30a 6 18701917
hsa-miR-30a* hsa-mir-30a 6 18701917
hsa-miR-30b hsa-mir-30b 8 18701917
hsa-miR-30b* hsa-mir-30b 8 18701917
hsa-miR-30c hsa-mir-30c-2 6 18701917
hsa-miR-30c hsa-mir-30c-1 1 18701917
hsa-miR-30c-1* hsa-mir-30c-1 1 18701917
hsa-miR-30c-2* hsa-mir-30c-2 6 18701917
hsa-miR-30d hsa-mir-30d 8 18701917
hsa-miR-30d* hsa-mir-30d 8 18701917
hsa-miR-30e hsa-mir-30e 1 18701917
hsa-miR-30e* hsa-mir-30e 1 18701917
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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