AutismKB 2.0

Annotation Detail for OAS3


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:OAS3 ( MGC133260,p100 )
Gene Full Name: 2'-5'-oligoadenylate synthetase 3, 100kDa
Band: 12q24.13
Quick LinksEntrez ID:4940; OMIM: 603351; Uniprot ID:OAS3_HUMAN; ENSEMBL ID: ENSG00000111331; HGNC ID: 8088
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
1N-acetylmethionine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
65MethylarginineHMM predict
104Phosphoserine(PKA)HMM predict
104Phosphoserine(PKG)HMM predict
365Phosphothreonine(MAPK)HMM predict
381PhosphoserineHMM predict
381Phosphoserine(IKK)HMM predict
385Phosphoserine(IKK)HMM predict
396O-linkedHMM predict
396O-linkedHMM predict
400O-linkedHMM predict
409Phosphoserine(ATM)HMM predict
427Phosphoserine(CDC2)HMM predict
675N-linkedHMM predict
874Phosphoserine(CK1)HMM predict
965Phosphoserine(PKG)HMM predict
1070CysteineHMM predict
1074AsparagineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_006187
  • Location:chr12 111860631-111895434
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
FOXA1 MCF7GSE15244 111855189 111855404 215 5335
FOXA1 MCF7GSE15244 111860228 111860917 689 59
NFkBII GM12878GSE19485 111859747 111861201 1454 158
NFkBII GM18526GSE19485 111859849 111861209 1360 103
NRSF mAbJurkat 111859072 111860490 1418 851
NRSF-poly JurkatQuESTdata 111859859 111860965 1106 220
Nanog hESGSE18292 111854896 111855280 384 5544
RARA MCF7GSE15244 111855189 111855404 215 5335
RARA MCF7GSE15244 111858819 111860596 1777 924
RARG MCF7GSE15244 111853168 111853356 188 7370
RARG MCF7GSE15244 111858855 111859686 831 1361
Rb GrowingGSE19898 111860500 111860704 204 30
p130 QuiescentGSE19898 111860282 111860732 450 125
p130 SenescentGSE19898 111860321 111860780 459 81
p130 shRbQuiescentGSE19898 111860246 111860858 612 80
p130 shRbSenescentGSE19898 111860255 111860968 713 20
p63 keratinocytesGSE17611 111858195 111859802 1607 1633
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 111872718 111872899 181 0
CTCF G2GSE9613 111886238 111886748 510 0
CTCF G2GSE9613 111887670 111888231 561 0
CTCF G2GSE9613 111891659 111892067 408 0
CTCF G2GSE9613 111893323 111893610 287 0
CTCF G2GSE9613 111894059 111894262 203 0
E2F4 G0GSE7516 111860414 111860850 436 0
Fos K562GSE19551 111883239 111883761 522 0
LIN9 G0GSE7516 111860338 111860952 614 0
NRSF pAbJurkat 111886543 111886748 205 0
Oct1 HelaGSE14283 111886138 111886175 37 0
Rb QuiescentGSE19898 111860520 111860743 223 0
Rb SenescentGSE19898 111860440 111860874 434 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018