AutismKB 2.0

Annotation Detail for OGDH


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Basic Information Top
Gene Symbol:OGDH ( AKGDH,E1k,OGDC )
Gene Full Name: oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
Band: 7p13
Quick LinksEntrez ID:4967; OMIM: 613022; Uniprot ID:ODO1_HUMAN; ENSEMBL ID: ENSG00000105953; HGNC ID: 8124
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
970N6-acetyllysine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
57Phosphotyrosine(INSR)HMM predict
93Phosphotyrosine(Abl)HMM predict
100O-linkedHMM predict
160Phosphoserine(ATM)HMM predict
365N-linkedHMM predict
388Phosphothreonine(CK2)HMM predict
555Phosphotyrosine(EGFR)HMM predict
555Phosphotyrosine(INSR)HMM predict
555SulfotyrosineHMM predict
560Phosphoserine(CK1)HMM predict
603Phosphoserine(PKB)HMM predict
603Phosphoserine(IKK)HMM predict
628N-linkedHMM predict
648N-linkedHMM predict
717N-linkedHMM predict
721Phosphoserine(CK1)HMM predict
723Phosphotyrosine(INSR)HMM predict
831N-linkedHMM predict
834Phosphothreonine(MAPK)HMM predict
837N-linkedHMM predict
871Phosphoserine(IKK)HMM predict
975Phosphothreonine(PKA)HMM predict
988ArginineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001003941
  • Location:chr7 44612695-44682718
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 44607393 44607640 247 5179
Oct1 HelaGSE14283 44608197 44608283 86 4456
hScc1 BcellGSE12603 44612413 44612842 429 68
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 44612744 44612877 133 0
CTCF G2GSE9613 44630581 44630858 277 0
CTCF G2GSE9613 44635537 44635664 127 0
CTCF G2GSE9613 44641309 44641496 187 0
CTCF G2GSE9613 44680076 44680775 699 0
ETS1 JurkatGSE17954 44612217 44613529 1312 0
Fos K562GSE19551 44612181 44613840 1659 0
Fos K562GSE19551 44645189 44645765 576 0
H3K4me2 HCT116GSE10453 44613423 44613796 373 0
H3ac HepG2E 44613423 44613796 373 0
Oct1 HelaGSE14283 44624155 44624225 70 0
Oct1 HelaGSE14283 44680102 44680173 71 0
Oct4 hESGSE17917 44681125 44681406 281 0
PHF8 HeLaGSE20725 44612182 44613769 1587 0
Rb QuiescentGSE19898 44613010 44613489 479 0
Rb SenescentGSE19898 44613092 44613428 336 0
Rb shRbSenescenceGSE19898 44612936 44613327 391 0
TFAP2C MCF7GSE21234 44641399 44641702 303 0
USF1 HepG2E 44613229 44613796 567 0
USF2 HepG2E 44613459 44613796 337 0
hScc1 CdLSGSE12603 44645211 44645775 564 0
p130 SenescentGSE19898 44613078 44613510 432 0
p130 shRbQuiescentGSE19898 44612896 44613613 717 0
p130 shRbSenescentGSE19898 44612988 44613480 492 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018