AutismKB 2.0

Annotation Detail for P2RX5


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Basic Information Top
Gene Symbol:P2RX5 ( LRH-1,MGC47755,P2X5,P2X5R )
Gene Full Name: purinergic receptor P2X, ligand-gated ion channel, 5
Band: 17p13.2
Quick LinksEntrez ID:5026; OMIM: 602836; Uniprot ID:P2RX5_HUMAN; ENSEMBL ID: ENSG00000083454; HGNC ID: 8536
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
55Phosphotyrosine.
77N-linked (GlcNAc...) (Potential).
202N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
77N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
202N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
55Phosphotyrosine(Syk)HMM predict
77N-linkedHMM predict
110Phosphothreonine(CDK)HMM predict
149Phosphothreonine(PKC)HMM predict
214PhosphoserineHMM predict
350Phosphotyrosine(Jak)HMM predict
350Phosphotyrosine(Syk)HMM predict
360Phosphoserine(ATM)HMM predict
360Phosphoserine(CK1)HMM predict
403Phosphoserine(ATM)HMM predict
407N-linkedHMM predict
411S-farnesylHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_002561
  • Location:chr17 3523272-3546331
  • strand:-
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Oct1 HelaGSE14283 3521547 3521576 29 1711
Oct1 HelaGSE14283 3521617 3521646 29 1641
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 3533073 3533524 451 0
CTCF CD4SISSRdata 3533073 3533524 451 0
CTCF G2GSE9613 3527923 3528272 349 0
CTCF G2GSE9613 3533099 3533459 360 0
CTCF G2GSE9613 3535307 3537950 2643 0
H3ac HepG2E 3529863 3531161 1298 0
Oct1 HelaGSE14283 3535341 3535372 31 0
Oct1 HelaGSE14283 3537666 3537715 49 0
hScc1 BcellGSE12603 3529863 3531551 1688 0
hScc1 BcellGSE12603 3533099 3533459 360 0
hScc1 BcellGSE12603 3535687 3538091 2404 0
hScc1 CdLSGSE12603 3533099 3533459 360 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018