Annotation Detail for PAFAH1B2

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Basic Information Top

Gene Symbol:	PAFAH1B2 ( - )
Gene Full Name:	platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
Band:	11q23
Quick Links	Entrez ID:5049; OMIM: 602508; Uniprot ID:PA1B2_HUMAN; ENSEMBL ID: ENSG00000168092; HGNC ID: 8575
Relate to Another Database:	SFARIGene; denovo-db

Post Translation Modification

Location(AA)	Modification
2	Phosphoserine.

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
ER	E2-MCF7	GSE14664	116515100	116515144	44	5128
ER	Fulvestrant-MCF7	GSE14664	116515101	116515134	33	5132
FOXA1	DLD1	GSE12801	116515530	116515766	236	4602
GABP	k562	GSE8489	116519389	116520202	813	454
H3ac	HepG2	E	116513601	116514653	1052	6123
P300	T30-glioblastoma	GSE21026	116513017	116513733	716	6875
RNAII	Tamoxifen-MCF7	GSE14664	116515098	116515136	38	5133
TFAP2C	MCF7	GSE21234	116513073	116513583	510	6922

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
TFAP2C	MCF7	GSE21234	116548540	116549104	564	4799

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length
GABP	k562	GSE8489	116520893	116522004	1111
H3K4me3	colorectal	cancer	116521613	116522004	391
H3ac	HepG2	E	116520851	116522004	1153
Oct1	Hela	GSE14283	116525328	116525387	59
PHF8	293T	GSE20725	116519684	116521223	1539
PHF8	HeLa	GSE20725	116519818	116521144	1326
PolII	HeLa	GSE12783	116519366	116521610	2244

Validated miRNA targets

Micro RNA Name	Stem Loop Name	The chromosome that miRNA located	Publication
hsa-let-7b	hsa-let-7b	22	18668040
hsa-let-7b*	hsa-let-7b	22	18668040
hsa-miR-1	hsa-mir-1-2	18	18668040
hsa-miR-1	hsa-mir-1-1	20	18668040
hsa-miR-155	hsa-mir-155	21	18668040
hsa-miR-155*	hsa-mir-155	21	18668040
hsa-miR-16	hsa-mir-16-1	13	18668040
hsa-miR-16	hsa-mir-16-2	3	18668040
hsa-miR-30a	hsa-mir-30a	6	18668040
hsa-miR-30a*	hsa-mir-30a	6	18668040
hsa-miR-30b	hsa-mir-30b	8	18668040
hsa-miR-30b*	hsa-mir-30b	8	18668040
hsa-miR-30c	hsa-mir-30c-2	6	18668040
hsa-miR-30c	hsa-mir-30c-1	1	18668040
hsa-miR-30c-1*	hsa-mir-30c-1	1	18668040
hsa-miR-30c-2*	hsa-mir-30c-2	6	18668040
hsa-miR-30d	hsa-mir-30d	8	18668040
hsa-miR-30d*	hsa-mir-30d	8	18668040
hsa-miR-30e	hsa-mir-30e	1	18668040
hsa-miR-30e*	hsa-mir-30e	1	18668040

ID in Tarbase	Data Type	Support Type	miRNA	Gene	Direct Support	Publication
1077	Unknown	pSILAC	miR-16	PAFAH1B2	down 50-25%	18668040
1260	Unknown	pSILAC	miR-30	PAFAH1B2	down 50-25%	18668040
Ensembl	Protein Type	Differentially expressed in	Pathology or Event	Mis Regulation	Gene Expression	Tumour Involvement
ENSG00000168092		n_a	n_a	n_a	"lymphocyte, muscle cell"	"malignant tumour, carcinoma, leukaemia"
ENSG00000168092		n_a	n_a	n_a	"lymphocyte, muscle cell"	"malignant tumour, carcinoma, leukaemia"

Cis-Nats regulation

Simple Query:

Paper Collected: 6/30/2018

Last Update: 8/26/2018