AutismKB 2.0

Annotation Detail for ARHGEF4


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Basic Information Top
Gene Symbol:ARHGEF4 ( ASEF,ASEF1,GEF4,STM6 )
Gene Full Name: Rho guanine nucleotide exchange factor (GEF) 4
Band: 2q21.1
Quick LinksEntrez ID:50649; OMIM: 605216; Uniprot ID:ARHG4_HUMAN; ENSEMBL ID: ENSG00000136002; HGNC ID: 684
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
20Phosphoserine(ATM)HMM predict
90Phosphoserine(IKK)HMM predict
90Phosphoserine(ATM)HMM predict
127Phosphoserine(CK2)HMM predict
127Phosphoserine(CK1)HMM predict
132Phosphotyrosine(SRC)HMM predict
132SulfotyrosineHMM predict
132Phosphotyrosine(Syk)HMM predict
137Phosphoserine(CK1)HMM predict
142Phosphotyrosine(Jak)HMM predict
142Phosphotyrosine(INSR)HMM predict
235Phosphoserine(CK2)HMM predict
246Phosphoserine(CK1)HMM predict
247Phosphoserine(IKK)HMM predict
266Phosphotyrosine(EGFR)HMM predict
289Phosphoserine(CK1)HMM predict
304Phosphotyrosine(Jak)HMM predict
407Phosphotyrosine(INSR)HMM predict
596N-linkedHMM predict
642ProlineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_032995
  • Location:chr2 131390693-131521305
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 131371179 131371473 294 19368
CTCF G2GSE9613 131375053 131375279 226 15528
CTCF G2GSE9613 131385958 131386239 281 4595
CTCF G2GSE9613 131390151 131390402 251 417
hScc1 BcellGSE12603 131390114 131391123 1009 75
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 131394461 131394839 378 0
CTCF CD4SISSRdata 131394461 131394839 378 0
CTCF G2GSE9613 131390730 131391275 545 0
CTCF G2GSE9613 131392486 131392687 201 0
CTCF G2GSE9613 131394369 131394789 420 0
CTCF G2GSE9613 131405063 131405501 438 0
CTCF G2GSE9613 131421863 131422108 245 0
CTCF G2GSE9613 131435097 131435671 574 0
CTCF G2GSE9613 131437209 131438561 1352 0
CTCF G2GSE9613 131439669 131440190 521 0
CTCF G2GSE9613 131489949 131490375 426 0
CTCF G2GSE9613 131501888 131502038 150 0
CTCF G2GSE9613 131504556 131504989 433 0
CTCF G2GSE9613 131508818 131509319 501 0
CTCF G2GSE9613 131510692 131511125 433 0
CTCF G2GSE9613 131511445 131511808 363 0
CTCF G2GSE9613 131512146 131513091 945 0
CTCF G2GSE9613 131513761 131514836 1075 0
CTCF G2GSE9613 131517652 131519478 1826 0
CTCF G2GSE9613 131519937 131521785 1848 0
Nanog hESGSE18292 131407888 131408301 413 0
Oct1 HelaGSE14283 131422259 131422294 35 0
Oct1 HelaGSE14283 131467621 131467661 40 0
TFAP2C MCF7GSE21234 131424075 131424378 303 0
TFAP2C MCF7GSE21234 131478662 131479621 959 0
TFAP2C MCF7GSE21234 131507780 131508705 925 0
hScc1 BcellGSE12603 131392486 131392687 201 0
hScc1 BcellGSE12603 131394369 131394686 317 0
hScc1 BcellGSE12603 131437428 131438215 787 0
hScc1 BcellGSE12603 131508702 131509284 582 0
hScc1 BcellGSE12603 131512176 131512622 446 0
hScc1 BcellGSE12603 131513684 131514577 893 0
hScc1 BcellGSE12603 131518455 131518784 329 0
hScc1 BcellGSE12603 131520160 131520390 230 0
hScc1 G2GSE9613 131394369 131394820 451 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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