AutismKB 2.0

Annotation Detail for PARK2


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Basic Information Top
Gene Symbol:PARK2 ( AR-JP,LPRS2,PDJ,PRKN )
Gene Full Name: parkinson protein 2, E3 ubiquitin protein ligase (parkin)
Band: 6q25.2-q27
Quick LinksEntrez ID:5071; OMIM: 602544; Uniprot ID:PRKN2_HUMAN; ENSEMBL ID: ENSG00000185345; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
19Phosphoserine(CK1)HMM predict
81N-linkedHMM predict
131Phosphoserine(PKA)HMM predict
131Phosphoserine(IKK)HMM predict
136Phosphoserine(CDC2)HMM predict
136Phosphoserine(CDK)HMM predict
143Phosphotyrosine(EGFR)HMM predict
173Phosphothreonine(PKA)HMM predict
235N-linkedHMM predict
312Phosphotyrosine(Syk)HMM predict
391Phosphotyrosine(Jak)HMM predict
449CysteineHMM predict
457S-farnesylHMM predict
457CysteineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_004562
  • Location:chr6 161689663-163068789
  • strand:-
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
RARA MCF7GSE15244 161683087 161683475 388 6383
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T0-glioblastomaGSE21026 162162271 162162793 522 0
CBP T0-glioblastomaGSE21026 162894682 162895315 633 0
CBP T30-glioblastomaGSE21026 162162347 162162903 556 0
CBP T30-glioblastomaGSE21026 162440515 162441160 645 0
CTCF CD4GSE12889 161711902 161712155 253 0
CTCF CD4GSE12889 161714895 161715232 337 0
CTCF CD4GSE12889 161734838 161735115 277 0
CTCF CD4GSE12889 161759447 161759776 329 0
CTCF CD4SISSRdata 161711902 161712155 253 0
CTCF CD4SISSRdata 161714895 161715232 337 0
CTCF CD4SISSRdata 161734838 161735115 277 0
CTCF CD4SISSRdata 161759447 161759776 329 0
CTCF HelaGSE12889 161734965 161735158 193 0
CTCF HelaGSE12889 161759471 161759697 226 0
CTCF HelaGSE12889 162001959 162002139 180 0
CTCF JurkatGSE12889 161711902 161712236 334 0
CTCF G2GSE9613 161697206 161697419 213 0
CTCF G2GSE9613 161702721 161702967 246 0
CTCF G2GSE9613 161709606 161709949 343 0
CTCF G2GSE9613 161711676 161712143 467 0
CTCF G2GSE9613 161714555 161715050 495 0
CTCF G2GSE9613 161716036 161716418 382 0
CTCF G2GSE9613 161734918 161735202 284 0
CTCF G2GSE9613 161754846 161755134 288 0
CTCF G2GSE9613 161859174 161859649 475 0
CTCF G2GSE9613 161898600 161898826 226 0
CTCF G2GSE9613 161934546 161934860 314 0
CTCF G2GSE9613 161977075 161977218 143 0
CTCF G2GSE9613 161987058 161987425 367 0
CTCF G2GSE9613 162001814 162001998 184 0
CTCF G2GSE9613 162014116 162014556 440 0
CTCF G2GSE9613 162020283 162020734 451 0
CTCF G2GSE9613 162036056 162036273 217 0
CTCF G2GSE9613 162089447 162089584 137 0
CTCF G2GSE9613 162154417 162154565 148 0
CTCF G2GSE9613 162179596 162179977 381 0
CTCF G2GSE9613 162181133 162181446 313 0
CTCF G2GSE9613 162245653 162246016 363 0
CTCF G2GSE9613 162294455 162294809 354 0
CTCF G2GSE9613 162392390 162392607 217 0
CTCF G2GSE9613 162396521 162396851 330 0
CTCF G2GSE9613 162513283 162513433 150 0
CTCF G2GSE9613 162547289 162547550 261 0
CTCF G2GSE9613 162651242 162651443 201 0
CTCF G2GSE9613 162717603 162717999 396 0
CTCF G2GSE9613 162758113 162758440 327 0
CTCF G2GSE9613 162909332 162909643 311 0
CTCF G2GSE9613 162910204 162910707 503 0
ETS1 JurkatGSE17954 162780199 162780525 326 0
FOXA1 MCF7GSE15244 161890912 161891891 979 0
FOXA1 MCF7GSE15244 162677521 162678220 699 0
Fos K562GSE19551 161734897 161735328 431 0
Fos K562GSE19551 161779983 161780571 588 0
Fos K562GSE19551 162263811 162264236 425 0
FoxA1 MCF7MACSdata 161891337 161891708 371 0
H3K4me3 colorectalcancer 163067794 163068388 594 0
Jun K562GSE19551 162263888 162264264 376 0
Myc K562GSE19551 161694256 161694717 461 0
Myc K562GSE19551 162263885 162264205 320 0
Myc K562GSE19551 162705458 162705809 351 0
Nanog ESGSE20650 162068095 162068498 403 0
Nanog ESGSE20650 162791190 162791766 576 0
Nanog hESGSE18292 161784726 161785104 378 0
Nanog hESGSE18292 161824214 161824557 343 0
Nanog hESGSE18292 161898752 161898974 222 0
Nanog hESGSE18292 162529509 162529989 480 0
Nanog hESGSE18292 162967051 162967526 475 0
Oct4 hESGSE17917 162869003 162869157 154 0
P300 T30-glioblastomaGSE21026 161710162 161711006 844 0
P300 T30-glioblastomaGSE21026 161748442 161748951 509 0
P300 T30-glioblastomaGSE21026 161779859 161780858 999 0
P300 T30-glioblastomaGSE21026 162440625 162441267 642 0
Rb GrowingGSE19898 161714995 161715278 283 0
Sox2 hESGSE18292 161695595 161695834 239 0
Sox2 hESGSE18292 162966936 162967518 582 0
Stat6 IL-4-hr1GSE17850 162154182 162154771 589 0
Stat6 IL-4-hr4GSE17850 161960429 161961044 615 0
TAF k562GSE8489 162766922 162767175 253 0
TFAP2C MCF7GSE21234 161714884 161715550 666 0
TFAP2C MCF7GSE21234 162319666 162319968 302 0
TFAP2C MCF7GSE21234 162592331 162592614 283 0
TFAP2C MCF7GSE21234 162758132 162758539 407 0
USF1 HepG2E 162591242 162591662 420 0
USF2 HepG2E 162591242 162591662 420 0
VDR GM10855-stimGSE22484 161748056 161749334 1278 0
hScc1 BcellGSE12603 161709606 161709915 309 0
hScc1 BcellGSE12603 161711641 161712143 502 0
hScc1 BcellGSE12603 161714630 161715157 527 0
hScc1 BcellGSE12603 161715958 161716313 355 0
hScc1 BcellGSE12603 161759416 161759784 368 0
hScc1 BcellGSE12603 161859174 161859613 439 0
hScc1 BcellGSE12603 162001698 162001998 300 0
hScc1 BcellGSE12603 162036056 162036380 324 0
hScc1 BcellGSE12603 162154565 162154821 256 0
hScc1 BcellGSE12603 162253655 162253807 152 0
hScc1 BcellGSE12603 162712229 162712436 207 0
hScc1 BcellGSE12603 162910133 162910608 475 0
hScc1 CdLSGSE12603 161711641 161712143 502 0
hScc1 CdLSGSE12603 161714555 161715157 602 0
hScc1 CdLSGSE12603 161734730 161735346 616 0
hScc1 CdLSGSE12603 161759322 161760037 715 0
hScc1 CdLSGSE12603 163054005 163054222 217 0
hScc1 G2GSE9613 161711710 161712143 433 0
hScc1 G2GSE9613 161714414 161715157 743 0
hScc1 G2GSE9613 161734840 161735273 433 0
hScc1 G2GSE9613 162036056 162036237 181 0
p63 keratinocytesGSE17611 161747460 161748055 595 0
p63 keratinocytesGSE17611 161827149 161827726 577 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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