Annotation Detail for CLEC4A

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Basic Information Top

Gene Symbol:	CLEC4A ( CLECSF6,DCIR,DDB27,LLIR )
Gene Full Name:	C-type lectin domain family 4, member A
Band:	12p13.31
Quick Links	Entrez ID:50856; OMIM: 605306; Uniprot ID:CLC4A_HUMAN; ENSEMBL ID: ENSG00000111729; HGNC ID: 13257
Relate to Another Database:	SFARIGene; denovo-db

Pathways, Diseases and Drugs

TF binding site

Post Translation Modification

PTM Sites from Uniprot:2 results
Experimental PTM Sites from dbPTM:1 results
Predicted PTM Sites by profile HMM from dbPTM:14 results

Location(AA)	Modification
10	ITIM motif.
185	N-linked (GlcNAc...) (Potential).

Location(AA)	Modification	Resource
7	Phosphotyrosine(SRC)	HMM predict
23	O-linked	HMM predict
29	O-linked	HMM predict
29	Phosphoserine(CK1)	HMM predict
106	S-palmitoyl	HMM predict
168	Phosphoserine(ATM)	HMM predict
182	Phosphothreonine(MAPK)	HMM predict
182	Phosphothreonine(CDC2)	HMM predict
184	Phosphotyrosine(Syk)	HMM predict
185	N-linked	HMM predict
197	Phosphoserine(PKB)	HMM predict
211	Phosphoserine(CDC2)	HMM predict
222	S-farnesyl	HMM predict
227	Arginine	HMM predict

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

RefSeq ID: NM_016184
Location:chr12 8167494-8182469
strand:+

Upstream the gene:3 results
Downstream the gene:0 results
Inside the gene:2 results

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
NRSF	pAb	Jurkat	8166204	8166455	251	1165
Oct1	H2O2-Hela	GSE14283	8156494	8156528	34	10984
Oct1	Hela	GSE14283	8156494	8156527	33	10984

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CTCF	G2	GSE9613	8178474	8178722	248	0
hScc1	Bcell	GSE12603	8178503	8178722	219	0

Validated miRNA targets

Cis-Nats regulation

Cluster ID	Plue Type	Plus Gene Name	Plus Chromosome	Plus Start	Plus End	Overlap Length	Minus Type	Minus Gene Name	Minus Chromosome	Minus Star	Minus End	Type
5617	mRNA	CLEC4A	chr12	8167494	8182470	1081	mRNA		chr12	8177633	8178714	Non-exonic Bidirectional (NOB) pairs

Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

Studies: 1,036
Genes: 1,379
CNVs/SVs: 5,420
SNVs/Indels: 11,669
de novo Mutations: 5,669
Mosaics: 789
Linkage Regions: 172

Paper Collected: 6/30/2018

Last Update: 8/26/2018

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