AutismKB 2.0

Annotation Detail for PBX2


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Basic Information Top
Gene Symbol:PBX2 ( G17,HOX12,PBX2MHC )
Gene Full Name: pre-B-cell leukemia homeobox 2
Band: 6p21.32
Quick LinksEntrez ID:5089; OMIM: 176311; Uniprot ID:PBX2_HUMAN; ENSEMBL ID: ENSG00000204304; HGNC ID: 8633
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
105Phosphoserine.
151Phosphoserine.
330Phosphoserine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
15MethylarginineHMM predict
105Phosphoserine(ATM)HMM predict
105Phosphoserine(PKG)HMM predict
105Phosphoserine(CK2)HMM predict
146O-linkedHMM predict
146O-linkedHMM predict
155Phosphoserine(CK1)HMM predict
174Phosphoserine(CK2)HMM predict
220Phosphoserine(PKA)HMM predict
250N-linkedHMM predict
264Phosphotyrosine(Jak)HMM predict
325O-linkedHMM predict
330O-linkedHMM predict
332O-linkedHMM predict
333Phosphoserine(CK1)HMM predict
333O-linkedHMM predict
334Phosphoserine(PKB)HMM predict
334Phosphoserine(IKK)HMM predict
334Phosphoserine(CDC2)HMM predict
336O-linkedHMM predict
336Phosphothreonine(CDK)HMM predict
336Phosphothreonine(MAPK)HMM predict
336O-linkedHMM predict
339Phosphoserine(CDC2)HMM predict
348N-linkedHMM predict
350Phosphoserine(CK2)HMM predict
370Phosphoserine(ATM)HMM predict
370Phosphoserine(IKK)HMM predict
395Phosphoserine(ATM)HMM predict
402N-linkedHMM predict
410Phosphothreonine(MAPK)HMM predict
410O-linkedHMM predict
412O-linkedHMM predict
413O-linkedHMM predict
415O-linkedHMM predict
416Phosphoserine(CDC2)HMM predict
418O-linkedHMM predict
423Phosphoserine(ATM)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_002586
  • Location:chr6 32260495-32265940
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
NFkBII GM10847GSE19485 32265420 32266748 1328 144
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 32263967 32264158 191 0
CTCF G2GSE9613 32264688 32264936 248 0
CTCF G2GSE9613 32265653 32266134 481 0
H3K4me3 colorectalcancer 32264827 32265245 418 0
H3ac HepG2E 32261984 32263748 1764 0
H3ac HepG2E 32264196 32265515 1319 0
KLF4 hESGSE17917 32265611 32266108 497 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018