AutismKB 2.0

Annotation Detail for PBX3


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Basic Information Top
Gene Symbol:PBX3 ( - )
Gene Full Name: pre-B-cell leukemia homeobox 3
Band: 9q33.3
Quick LinksEntrez ID:5090; OMIM: 176312; Uniprot ID:PBX3_HUMAN; ENSEMBL ID: ENSG00000167081; HGNC ID: 8634
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
121Phosphoserine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
139O-linkedHMM predict
143Phosphoserine(ATM)HMM predict
146Phosphoserine(CK1)HMM predict
195Phosphoserine(ATM)HMM predict
211Phosphoserine(PKA)HMM predict
212Phosphoserine(PKA)HMM predict
241N-linkedHMM predict
255Phosphotyrosine(Jak)HMM predict
314O-linkedHMM predict
326N-linkedHMM predict
329N-linkedHMM predict
330Phosphoserine(CDC2)HMM predict
330Phosphoserine(IKK)HMM predict
332O-linkedHMM predict
333Phosphothreonine(CDK)HMM predict
333Phosphothreonine(CDC2)HMM predict
333O-linkedHMM predict
341Phosphoserine(IKK)HMM predict
377Phosphothreonine(PKC)HMM predict
383N-linkedHMM predict
414Phosphothreonine(MAPK)HMM predict
416O-linkedHMM predict
417Phosphoserine(IKK)HMM predict
419O-linkedHMM predict
420Phosphoserine(CDC2)HMM predict
422O-linkedHMM predict
427Phosphoserine(ATM)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_006195
  • Location:chr9 127549486-127769473
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
LIN9 G0GSE7516 127547878 127548486 608 1305
NRSF JurkatGSE13047 127534645 127535050 405 14639
NRSF JurkatSISSRdata 127534768 127534933 165 14636
NRSF-mono JurkatQuESTdata 127534649 127535049 400 14638
NRSF-poly JurkatQuESTdata 127534569 127535090 521 14657
TAF HelaGSE8489 127534195 127534366 171 15206
TFAP2C MCF7GSE21234 127534545 127535217 672 14606
hScc1 BcellGSE12603 127548142 127548381 239 1225
hScc1 BcellGSE12603 127548711 127549168 457 547
p130 SenescentGSE19898 127548055 127548655 600 1132
p130 shRbSenescentGSE19898 127547924 127548655 731 1197
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
p63 keratinocytesGSE17611 127772086 127773030 944 3085
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T0-glioblastomaGSE21026 127745085 127745889 804 0
Nanog ESGSE20650 127680471 127681071 600 0
Nanog ESGSE20650 127753130 127753752 622 0
Oct4 hESGSE17917 127753328 127753686 358 0
P300 T0-glioblastomaGSE21026 127561119 127561603 484 0
P300 T30-glioblastomaGSE21026 127560912 127561801 889 0
P300 T30-glioblastomaGSE21026 127733942 127734726 784 0
Rb QuiescentGSE19898 127692141 127692275 134 0
hScc1 BcellGSE12603 127550063 127550540 477 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018