AutismKB 2.0

Annotation Detail for PCCB


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Basic Information Top
Gene Symbol:PCCB ( DKFZp451E113 )
Gene Full Name: propionyl CoA carboxylase, beta polypeptide
Band: 3q22.3
Quick LinksEntrez ID:5096; OMIM: 232050; Uniprot ID:PCCB_HUMAN; ENSEMBL ID: ENSG00000114054; HGNC ID: 8654
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
60N6-acetyllysine (By similarity).
Location(AA) Modifications Resource
60N6-acetyllysine (By similarity).Swiss-Prot 53.0
Location(AA) Modification Resource
15Phosphoserine(PKG)HMM predict
30Phosphoserine(ATM)HMM predict
78Phosphoserine(IKK)HMM predict
183N-linkedHMM predict
282Phosphoserine(ATM)HMM predict
314Phosphotyrosine(Syk)HMM predict
439Phosphotyrosine(INSR)HMM predict
511Phosphothreonine(PKC)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_000532
  • Location:chr3 137451837-137531693
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Oct1 HelaGSE14283 137441513 137441545 32 10309
P300 T30-glioblastomaGSE21026 137433763 137434486 723 17713
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Myc K562GSE19551 137532545 137532874 329 1016
Rb shRbQuiescentGSE19898 137534947 137535130 183 3345
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 137507516 137507642 126 0
CTCF CD4SISSRdata 137507516 137507642 126 0
CTCF G2GSE9613 137451620 137452133 513 0
CTCF G2GSE9613 137464102 137464425 323 0
FOXA1 MCF7GSE15244 137452027 137452948 921 0
FoxA1 MCF7MACSdata 137468092 137468288 196 0
H3ac HepG2E 137456722 137457276 554 0
KLF4 hESGSE17917 137531001 137531431 430 0
Myc hESGSE17917 137451695 137452060 365 0
Nanog ESGSE20650 137498468 137498982 514 0
Oct4 hESGSE17917 137451684 137452181 497 0
Oct4 hESGSE21916 137498379 137498945 566 0
PHF8 HeLaGSE20725 137451544 137452614 1070 0
PHF8 Hs68minusFBSGSE20725 137451628 137452393 765 0
Sox2 hESGSE18292 137498588 137498779 191 0
TFAP2C MCF7GSE21234 137478966 137479743 777 0
TFAP2C MCF7GSE21234 137497227 137497677 450 0
hScc1 BcellGSE12603 137451620 137452176 556 0
hScc1 CdLSGSE12603 137451620 137453379 1759 0
hScc1 G2GSE9613 137451620 137452176 556 0
p130 SenescentGSE19898 137451787 137452231 444 0
p63 keratinocytesGSE17611 137477727 137478543 816 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
18723 mRNA PCCB chr3 137451897 137539435 739 mRNA STAG1 chr3 137538696 137953943Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018