AutismKB 2.0

Annotation Detail for PCDH8


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Basic Information Top
Gene Symbol:PCDH8 ( ARCADLIN,PAPC )
Gene Full Name: protocadherin 8
Band: 13q14.3
Quick LinksEntrez ID:5100; OMIM: 603580; Uniprot ID:PCDH8_HUMAN; ENSEMBL ID: ENSG00000136099; HGNC ID: 8660
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
70N-linked (GlcNAc...) (Potential).
464N-linked (GlcNAc...) (Potential).
616N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
70N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
464N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
616N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
70N-linkedHMM predict
112Phosphoserine(ATM)HMM predict
171Phosphothreonine(PKC)HMM predict
228Phosphothreonine(PKA)HMM predict
289PhosphothreonineHMM predict
289Phosphothreonine(MAPK)HMM predict
357O-linkedHMM predict
368O-linkedHMM predict
386O-linkedHMM predict
464N-linkedHMM predict
479Phosphothreonine(PKC)HMM predict
518Phosphothreonine(PKC)HMM predict
550Phosphothreonine(PKC)HMM predict
569Phosphotyrosine(Jak)HMM predict
678Phosphoserine(ATM)HMM predict
701O-linkedHMM predict
702O-linkedHMM predict
703O-linkedHMM predict
705O-linkedHMM predict
707O-linkedHMM predict
723O-linkedHMM predict
723O-linkedHMM predict
726Phosphoserine(CDC2)HMM predict
730O-linkedHMM predict
800O-linkedHMM predict
804Phosphoserine(IKK)HMM predict
852O-linkedHMM predict
852Phosphoserine(IKK)HMM predict
882Phosphoserine(CDC2)HMM predict
925N-linkedHMM predict
929Phosphoserine(CK1)HMM predict
977Phosphoserine(CDK)HMM predict
977O-linkedHMM predict
1004Phosphotyrosine(Syk)HMM predict
1018Phosphotyrosine(Syk)HMM predict
1034Phosphoserine(CDC2)HMM predict
1054Phosphoserine(CDK)HMM predict
1054Phosphoserine(CDC2)HMM predict
1059TyrosineHMM predict
1061Phosphoserine(CDC2)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_002590
  • Location:chr13 52316111-52320774
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 52322237 52323662 1425 2175
CTCF G2GSE9613 52334365 52334804 439 13810
H3K27me3 colorectalcancer 52321008 52322549 1541 1004
H3K4me3 colorectalcancer 52323623 52324218 595 3146
NRSF JurkatGSE13047 52322422 52323254 832 2064
NRSF mAbJurkat 52321479 52322585 1106 1258
NRSF-mono JurkatQuESTdata 52322564 52323253 689 2134
NRSF-poly JurkatQuESTdata 52322422 52323277 855 2075
Nanog hESGSE18292 52334610 52334851 241 13956
USF1 HepG2E 52323709 52324789 1080 3475
hScc1 BcellGSE12603 52322935 52323877 942 2632
hScc1 CdLSGSE12603 52322750 52324164 1414 2683
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Oct1 H2O2-HelaGSE14283 52309526 52309564 38 6567
Oct1 HelaGSE14283 52309523 52309564 41 6568
Sox2 hESGSE18292 52304797 52305096 299 11165
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 52316883 52317017 134 0
CTCF G2GSE9613 52317429 52318712 1283 0
CTCF G2GSE9613 52319158 52320682 1524 0
NRSF JurkatGSE13047 52318918 52319840 922 0
NRSF-mono JurkatQuESTdata 52318321 52319655 1334 0
NRSF-poly JurkatQuESTdata 52318891 52319840 949 0
Rb GrowingGSE19898 52317447 52317625 178 0
hScc1 BcellGSE12603 52317682 52318512 830 0
hScc1 BcellGSE12603 52318938 52320466 1528 0
hScc1 CdLSGSE12603 52317429 52318787 1358 0
hScc1 G2GSE9613 52317577 52318260 683 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-125a-3p hsa-mir-125a 19 16331254
hsa-miR-125a-5p hsa-mir-125a 19 16331254
hsa-miR-195 hsa-mir-195 17 16331254
hsa-miR-195* hsa-mir-195 17 16331254
hsa-miR-200a hsa-mir-200a 1 16331254
hsa-miR-200a* hsa-mir-200a 1 16331254
hsa-miR-224 hsa-mir-224 X 16331254
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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