AutismKB 2.0

Annotation Detail for LAP3


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:LAP3 ( LAP,LAPEP,PEPS )
Gene Full Name: leucine aminopeptidase 3
Band: 4p15.32
Quick LinksEntrez ID:51056; OMIM: 170250; Uniprot ID:AMPL_HUMAN; ENSEMBL ID: ENSG00000002549; HGNC ID: 18449
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
33N-acetylthreonine (By similarity).
221N6-acetyllysine.
Location(AA) Modifications Resource
33N-acetylthreonine (By similarity).Swiss-Prot 53.0
Location(AA) Modification Resource
24Phosphoserine(PKA)HMM predict
28Phosphoserine(IKK)HMM predict
72N-linkedHMM predict
138Phosphoserine(CK1)HMM predict
174Phosphoserine(PKG)HMM predict
211Phosphothreonine(MAPK)HMM predict
227Phosphoserine(CK2)HMM predict
228Phosphoserine(CK1)HMM predict
314O-linkedHMM predict
410N-linkedHMM predict
416N-linkedHMM predict
497O-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_015907
  • Location:chr4 17188024-17218687
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
LIN9 G0GSE7516 17187676 17188078 402 148
LIN9 SGSE7516 17187676 17187984 308 195
TFAP2C MCF7GSE21234 17172308 17173323 1015 15209
USF2 HepG2E 17170439 17170890 451 17360
p130 QuiescentGSE19898 17187544 17187877 333 314
p130 SenescentGSE19898 17172310 17172626 316 15557
p130 SenescentGSE19898 17187518 17188087 569 222
p130 shRbQuiescentGSE19898 17187407 17187888 481 377
p130 shRbSenescentGSE19898 17187478 17188007 529 282
p130 G0GSE7516 17187676 17188048 372 163
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 17187676 17188477 801 0
CTCF G2GSE9613 17194287 17194856 569 0
CTCF G2GSE9613 17208289 17208689 400 0
CTCF G2GSE9613 17216364 17216725 361 0
H3K4me3 colorectalcancer 17188607 17189602 995 0
H3ac HepG2E 17188639 17189636 997 0
NFkBII GM15510GSE19485 17187665 17188788 1123 0
PHF8 HeLaGSE20725 17187388 17188715 1327 0
hScc1 BcellGSE12603 17187676 17188505 829 0
hScc1 G2GSE9613 17187676 17188607 931 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
19467 mRNA LAP3 chr4 17255195 17285859 20501 EST chr4 17265358 17292463 Non-exonic Bidirectional (NOB) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved