AutismKB 2.0

Annotation Detail for PCM1


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Basic Information Top
Gene Symbol:PCM1 ( PTC4 )
Gene Full Name: pericentriolar material 1
Band: 8p22
Quick LinksEntrez ID:5108; OMIM: 600299; Uniprot ID:PCM1_HUMAN; ENSEMBL ID: ENSG00000078674; HGNC ID: 8727
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
61Phosphothreonine.
65Phosphoserine.
68Phosphoserine.
69Phosphoserine.
93Phosphoserine.
110Phosphoserine.
116Phosphoserine.
119Phosphoserine.
159Phosphoserine.
356Phosphoserine.
372Phosphoserine.
399N6-acetyllysine.
431Phosphoserine.
861Phosphoserine.
866Phosphoserine.
869Phosphoserine.
872Phosphoserine.
877Phosphothreonine.
960Phosphoserine.
991Phosphoserine.
1185Phosphoserine.
1187Phosphoserine.
1188Phosphoserine.
1231Phosphoserine.
1257Phosphoserine.
1260Phosphoserine.
1262Phosphoserine.
1290Phosphoserine (By similarity).
1373Phosphoserine.
1435Phosphoserine (By similarity).
1437Phosphoserine (By similarity).
1656Phosphoserine (By similarity).
1697Phosphoserine.
1730Phosphoserine.
1765Phosphoserine.
1768Phosphoserine.
1776Phosphoserine.
1977Phosphoserine.
2023Phosphoserine.
Location(AA) Modifications Resource
65Phosphoserine.Swiss-Prot 53.0
65PhosphoserinePhospho.ELM 6.0
68PhosphoserinePhospho.ELM 6.0
68Phosphoserine.Swiss-Prot 53.0
69Phosphoserine.Swiss-Prot 53.0
69PhosphoserinePhospho.ELM 6.0
110Phosphoserine.Swiss-Prot 53.0
110PhosphoserinePhospho.ELM 6.0
385PhosphoserinePhospho.ELM 6.0
387PhosphoserinePhospho.ELM 6.0
431Phosphoserine.Swiss-Prot 53.0
432PhosphoserinePhospho.ELM 6.0
861Phosphoserine.Swiss-Prot 53.0
862PhosphoserinePhospho.ELM 6.0
866Phosphoserine.Swiss-Prot 53.0
869Phosphoserine.Swiss-Prot 53.0
872Phosphoserine.Swiss-Prot 53.0
877Phosphothreonine.Swiss-Prot 53.0
991Phosphoserine.Swiss-Prot 53.0
992PhosphoserinePhospho.ELM 6.0
1257PhosphoserinePhospho.ELM 6.0
1260PhosphoserinePhospho.ELM 6.0
1494PhosphoserinePhospho.ELM 6.0
1497PhosphoserinePhospho.ELM 6.0
1499PhosphoserinePhospho.ELM 6.0
1500PhosphoserinePhospho.ELM 6.0
1729Phosphoserine.Swiss-Prot 53.0
1730PhosphoserinePhospho.ELM 6.0
1764Phosphoserine.Swiss-Prot 53.0
1765PhosphoserinePhospho.ELM 6.0
1767Phosphoserine.Swiss-Prot 53.0
1768PhosphoserinePhospho.ELM 6.0
1775Phosphoserine.Swiss-Prot 53.0
Location(AA) Modification Resource
19N-linkedHMM predict
22N-linkedHMM predict
24N-linkedHMM predict
42N-linkedHMM predict
48N-linkedHMM predict
61Phosphothreonine(PKA)HMM predict
65Phosphoserine(ATM)HMM predict
69Phosphoserine(ATM)HMM predict
93Phosphoserine(IKK)HMM predict
151N-linkedHMM predict
157Phosphoserine(IKK)HMM predict
159Phosphoserine(CDK)HMM predict
203Phosphoserine(ATM)HMM predict
356Phosphoserine(ATM)HMM predict
370Phosphoserine(IKK)HMM predict
372Phosphoserine(CK1)HMM predict
378Phosphoserine(CAMK2)HMM predict
384Phosphoserine(PKA)HMM predict
384Phosphoserine(PKG)HMM predict
384PhosphoserineHMM predict
426N-linkedHMM predict
427N-linkedHMM predict
431Phosphoserine(CDC2)HMM predict
431Phosphoserine(CDK)HMM predict
435Phosphoserine(PKA)HMM predict
442Phosphoserine(PKB)HMM predict
442PhosphoserineHMM predict
445O-linkedHMM predict
460Phosphoserine(IKK)HMM predict
463O-linkedHMM predict
464Phosphoserine(ATM)HMM predict
474Phosphoserine(ATM)HMM predict
474Phosphoserine(IKK)HMM predict
533Phosphoserine(CK1)HMM predict
535Phosphotyrosine(EGFR)HMM predict
535Phosphotyrosine(INSR)HMM predict
535Phosphotyrosine(SRC)HMM predict
535Phosphotyrosine(Syk)HMM predict
537Phosphoserine(CK2)HMM predict
542Phosphoserine(CK1)HMM predict
586N-linkedHMM predict
591N-linkedHMM predict
694Phosphoserine(CK2)HMM predict
694Phosphoserine(IKK)HMM predict
700SulfotyrosineHMM predict
711N-linkedHMM predict
712N-linkedHMM predict
716N-linkedHMM predict
718N-linkedHMM predict
788Phosphotyrosine(SRC)HMM predict
795O-linkedHMM predict
804Phosphoserine(CK1)HMM predict
816Phosphoserine(IKK)HMM predict
861Phosphoserine(MAPK)HMM predict
907Phosphotyrosine(INSR)HMM predict
907Phosphotyrosine(Syk)HMM predict
930N-linkedHMM predict
944Phosphotyrosine(Jak)HMM predict
965Phosphotyrosine(Syk)HMM predict
1038Phosphotyrosine(SRC)HMM predict
1038Phosphotyrosine(Jak)HMM predict
1099O-linkedHMM predict
1099Phosphoserine(CK2)HMM predict
1100O-linkedHMM predict
1102O-linkedHMM predict
1106O-linkedHMM predict
1106Phosphoserine(MAPK)HMM predict
1130N-linkedHMM predict
1152Phosphoserine(ATM)HMM predict
1154N-linkedHMM predict
1157Phosphothreonine(CDK)HMM predict
1175Phosphotyrosine(EGFR)HMM predict
1175Phosphotyrosine(Syk)HMM predict
1187Phosphoserine(CK1)HMM predict
1234Phosphoserine(IKK)HMM predict
1236Phosphoserine(CK1)HMM predict
1259Phosphoserine(IKK)HMM predict
1261O-linkedHMM predict
1262Phosphoserine(IKK)HMM predict
1282Phosphoserine(PKG)HMM predict
1282Phosphoserine(CAMK2)HMM predict
1282Phosphoserine(PKB)HMM predict
1286Phosphoserine(IKK)HMM predict
1293Phosphothreonine(CDC2)HMM predict
1293Phosphothreonine(MAPK)HMM predict
1293Phosphothreonine(CDK)HMM predict
1302N-linkedHMM predict
1334Phosphoserine(PKG)HMM predict
1337Phosphothreonine(PKC)HMM predict
1364Phosphothreonine(PKA)HMM predict
1367Phosphoserine(CK1)HMM predict
1368Phosphoserine(CK1)HMM predict
1385Phosphotyrosine(SRC)HMM predict
1393Phosphoserine(ATM)HMM predict
1395N-linkedHMM predict
1448Phosphoserine(CK1)HMM predict
1459Phosphothreonine(MAPK)HMM predict
1466Phosphothreonine(CK2)HMM predict
1496Phosphoserine(CK1)HMM predict
1531Phosphothreonine(PKC)HMM predict
1569N-linkedHMM predict
1577Phosphoserine(IKK)HMM predict
1617Phosphoserine(IKK)HMM predict
1750O-linkedHMM predict
1756Phosphotyrosine(Syk)HMM predict
1767Phosphoserine(CK2)HMM predict
1783N-linkedHMM predict
1795Phosphotyrosine(INSR)HMM predict
1797Phosphoserine(CK2)HMM predict
1893O-linkedHMM predict
1897O-linkedHMM predict
1897O-linkedHMM predict
1926Phosphothreonine(CDC2)HMM predict
1926Phosphothreonine(MAPK)HMM predict
1926Phosphothreonine(CDK)HMM predict
1934Phosphoserine(CDC2)HMM predict
1946Phosphotyrosine(Syk)HMM predict
1954Phosphoserine(ATM)HMM predict
1957Phosphoserine(CK2)HMM predict
1975Phosphotyrosine(INSR)HMM predict
2011Phosphothreonine(PKC)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_006197
  • Location:chr8 17824778-17929762
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 17816742 17816955 213 7930
CTCF G2GSE9613 17821192 17821473 281 3446
CTCF G2GSE9613 17824414 17824891 477 126
H3ac HepG2E 17816742 17817167 425 7824
H3ac HepG2E 17817954 17818533 579 6535
H3ac HepG2E 17823468 17824414 946 838
Myc K562GSE19551 17816540 17816889 349 8064
Nanog hESGSE18292 17813233 17813921 688 11202
PHF8 HeLaGSE20725 17823775 17825776 2001 3
PHF8 Hs68minusFBSGSE20725 17824046 17825415 1369 48
USF1 HepG2E 17823468 17824930 1462 580
USF2 HepG2E 17817954 17818293 339 6655
hScc1 BcellGSE12603 17821192 17821473 281 3446
hScc1 CdLSGSE12603 17816742 17817167 425 7824
hScc1 CdLSGSE12603 17821192 17821473 281 3446
hScc1 G2GSE9613 17816742 17817167 425 7824
hScc1 G2GSE9613 17821192 17821473 281 3446
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ER MCF7GSE19013 17824745 17825352 607 0
ETS1 JurkatGSE17954 17823898 17826117 2219 0
FOXA1 DLD1GSE12801 17869774 17870400 626 0
FOXA1 MCF7GSE15244 17904713 17905214 501 0
FoxA1 MCF7MACSdata 17904793 17905021 228 0
H3ac HepG2E 17824930 17826000 1070 0
H3ac HepG2E 17826324 17826943 619 0
H3ac HepG2E 17827654 17828531 877 0
PHF8 Hs68plusFBSGSE20725 17823924 17826085 2161 0
RARG MCF7GSE15244 17904713 17905214 501 0
hScc1 CdLSGSE12603 17824568 17825492 924 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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