AutismKB 2.0

Annotation Detail for KLHL5


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Basic Information Top
Gene Symbol:KLHL5 ( DKFZp586M1418,FLJ11313 )
Gene Full Name: kelch-like 5 (Drosophila)
Band: 4p14
Quick LinksEntrez ID:51088; OMIM: 608064; Uniprot ID:KLHL5_HUMAN; ENSEMBL ID: ENSG00000109790; HGNC ID: 6356
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
20O-linkedHMM predict
73Phosphoserine(IKK)HMM predict
73Phosphoserine(CDC2)HMM predict
75N-linkedHMM predict
76Phosphoserine(IKK)HMM predict
77O-linkedHMM predict
118Phosphoserine(PKG)HMM predict
132O-linkedHMM predict
162Phosphoserine(CK2)HMM predict
162Phosphoserine(CK1)HMM predict
166N-linkedHMM predict
168Phosphoserine(ATM)HMM predict
168Phosphoserine(CK2)HMM predict
168Phosphoserine(CK1)HMM predict
172Phosphoserine(IKK)HMM predict
177N-linkedHMM predict
179Phosphoserine(ATM)HMM predict
179O-linkedHMM predict
183Phosphoserine(IKK)HMM predict
187O-linkedHMM predict
303Phosphoserine(ATM)HMM predict
343N-linkedHMM predict
344Phosphotyrosine(Abl)HMM predict
465Phosphothreonine(PKA)HMM predict
564Phosphotyrosine(Abl)HMM predict
596O-linkedHMM predict
596Phosphothreonine(CDK)HMM predict
596Phosphothreonine(MAPK)HMM predict
669N-linkedHMM predict
724Phosphothreonine(PKC)HMM predict
745ArginineHMM predict
754LysineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001007075
  • Location:chr4 38723053-38800222
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 38720573 38720756 183 2389
FOXA1 MCF7GSE15244 38721194 38721829 635 1542
FOXA1 eGFPGSE10845 38721194 38721829 635 1542
FoxA1 MCF7MACSdata 38721360 38721572 212 1588
NFkBII GM12878GSE19485 38721204 38723187 1983 858
NFkBII GM12892GSE19485 38721480 38723271 1791 678
NFkBII GM15510GSE19485 38721148 38723313 2165 823
Oct1 H2O2-HelaGSE14283 38719369 38719402 33 3668
PHF8 Hs68plusFBSGSE20725 38721510 38723749 2239 424
PolII HeLaGSE12783 38721181 38724811 3630 58
RARA MCF7GSE15244 38721194 38721754 560 1580
hScc1 BcellGSE12603 38722376 38723508 1132 112
p130 QuiescentGSE19898 38722324 38722663 339 560
p130 SenescentGSE19898 38722426 38722619 193 531
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 38722476 38723768 1292 0
H3ac HepG2E 38723381 38724813 1432 0
NFkBII GM18526GSE19485 38721416 38724771 3355 0
Nanog ESGSE20650 38740196 38740568 372 0
Oct1 H2O2-HelaGSE14283 38736466 38736503 37 0
Oct1 HelaGSE14283 38736472 38736501 29 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
19582 mRNA KLHL5 chr4 38869224 38946395 213 EST chr4 38937064 38939809Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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