Annotation Detail for LACTB2

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Basic Information Top

Gene Symbol:	LACTB2 ( - )
Gene Full Name:	lactamase, beta 2
Band:	8q13.3
Quick Links	Entrez ID:51110; OMIM: NA; Uniprot ID:LACB2_HUMAN; ENSEMBL ID: ENSG00000147592; HGNC ID: 18512
Relate to Another Database:	SFARIGene; denovo-db

Pathways, Diseases and Drugs

TF binding site

Post Translation Modification

PTM Sites from Uniprot:2 results
Experimental PTM Sites from dbPTM:0 results
Predicted PTM Sites by profile HMM from dbPTM:0 results

Location(AA)	Modification
102	N6-acetyllysine (By similarity).
247	N6-acetyllysine.

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

RefSeq ID: NM_016027
Location:chr8 71712045-71743945
strand:-

Upstream the gene:4 results
Downstream the gene:1 results
Inside the gene:12 results

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
Oct4	hES	GSE21916	71743736	71744313	577	79
Rb	Senescent	GSE19898	71743536	71744356	820	1
TAFII	hES	GSE17917	71743643	71744296	653	24
p130	shRbSenescent	GSE19898	71743612	71744457	845	89

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
FOXA1	MCF7	GSE15244	71708676	71709004	328	3206

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CTCF	CD4	GSE12889	71743264	71743501	237	0
CTCF	CD4	SISSRdata	71743264	71743501	237	0
CTCF	G2	GSE9613	71743145	71743874	729	0
ER	E2-MCF7	GSE14664	71737682	71737716	34	0
ER	Fulvestrant-MCF7	GSE14664	71737679	71737716	37	0
Oct1	Hela	GSE14283	71732379	71732410	31	0
Oct1	Hela	GSE14283	71737684	71737716	32	0
PHF8	HeLa	GSE20725	71743477	71744364	887	0
PolII	HeLa	GSE12783	71743236	71744369	1133	0
USF2	HepG2	E	71743073	71743645	572	0
hScc1	Bcell	GSE12603	71742807	71743614	807	0
hScc1	CdLS	GSE12603	71742844	71744341	1497	0

Validated miRNA targets

Cis-Nats regulation

Cluster ID	Plue Type	Plus Gene Name	Plus Chromosome	Plus Start	Plus End	Overlap Length	Minus Type	Minus Gene Name	Minus Chromosome	Minus Star	Minus End	Type
25566	mRNA	LOC286190	chr8	71683365	71738067	164	mRNA	LACTB2	chr8	71712044	71743946	Sense/Antisense (SA) pairs

Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

Studies: 1,036
Genes: 1,379
CNVs/SVs: 5,420
SNVs/Indels: 11,669
de novo Mutations: 5,669
Mosaics: 789
Linkage Regions: 172

Paper Collected: 6/30/2018

Last Update: 8/26/2018

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