AutismKB 2.0

Annotation Detail for RAPGEFL1


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Basic Information Top
Gene Symbol:RAPGEFL1 ( Link-GEFII,MGC134798,MGC134799 )
Gene Full Name: Rap guanine nucleotide exchange factor (GEF)-like 1
Band: 17q21.1
Quick LinksEntrez ID:51195; OMIM: NA; Uniprot ID:RPGFL_HUMAN; ENSEMBL ID: ENSG00000108352; HGNC ID: 17428
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_016339
  • Location:chr17 35588138-35605425
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
FoxA1 MCF7MACSdata 35586214 35586341 127 1861
Rb GrowingGSE19898 35586865 35587040 175 1186
Rb GrowingGSE19898 35587099 35587195 96 992
Rb SenescentGSE19898 35586970 35587266 296 1021
p130 QuiescentGSE19898 35587081 35587206 125 995
p63 keratinocytesGSE17611 35586094 35587279 1185 1452
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 35611661 35611887 226 6349
CTCF CD4SISSRdata 35611661 35611887 226 6349
CTCF G2GSE9613 35611711 35611923 212 6392
ER Fulvestrant-MCF7GSE14664 35607433 35607467 34 2025
Fos K562GSE19551 35607739 35608230 491 2559
Oct1 HelaGSE14283 35607427 35607472 45 2024
hScc1 BcellGSE12603 35611711 35611923 212 6392
hScc1 CdLSGSE12603 35611711 35611923 212 6392
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 35601476 35601696 220 0
CTCF CD4SISSRdata 35601476 35601696 220 0
ER Fulvestrant-MCF7GSE14664 35588652 35588732 80 0
ER MCF7GSE19013 35590002 35590979 977 0
Rb GrowingGSE19898 35601602 35601710 108 0
Rb SenescentGSE19898 35589591 35589878 287 0
p130 QuiescentGSE19898 35601542 35601782 240 0
p63 keratinocytesGSE17611 35603605 35604699 1094 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018