Annotation Detail for NT5C3

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Basic Information Top

Gene Symbol:	NT5C3 ( MGC27337,MGC87109,MGC87828,P5'N-1,PN-I,PSN1,UMPH,UMPH1,cN-III )
Gene Full Name:	5'-nucleotidase, cytosolic III
Band:	7p14.3
Quick Links	Entrez ID:51251; OMIM: 606224; Uniprot ID:5NT3_HUMAN; ENSEMBL ID: ENSG00000122643; HGNC ID:
Relate to Another Database:	SFARIGene; denovo-db

Post Translation Modification

No data

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
ETS1	Jurkat	GSE17954	33068312	33069749	1437	97
PHF8	293T	GSE20725	33068323	33069982	1659	219
PHF8	Hs68minusFBS	GSE20725	33068618	33069816	1198	284
Rb	Quiescent	GSE19898	33069155	33069387	232	338
Rb	Senescent	GSE19898	33068813	33069132	319	39
p130	Quiescent	GSE19898	33069020	33069355	335	254
p130	shRbQuiescent	GSE19898	33068771	33069587	816	246
p130	shRbSenescent	GSE19898	33068818	33069338	520	145

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length
CTCF	CD4	GSE12889	33056861	33057268	407
CTCF	CD4	SISSRdata	33056861	33057268	407
CTCF	G2	GSE9613	33068401	33069007	606
ER	Fulvestrant-MCF7	GSE14664	33068693	33068732	39
H3K4me3	colorectal	cancer	33067772	33068448	676
Oct1	H2O2-Hela	GSE14283	33051423	33051463	40
Oct1	Hela	GSE14283	33051428	33051464	36
PHF8	HeLa	GSE20725	33068225	33069605	1380
Pol2	GM12878	GSE19551	33046794	33047331	537
Rb	Growing	GSE19898	33068270	33068421	151
Rb	Senescent	GSE19898	33068238	33068599	361
Rb	shRbSenescence	GSE19898	33068701	33069030	329
hScc1	Bcell	GSE12603	33056874	33057213	339
hScc1	Bcell	GSE12603	33068401	33068814	413
hScc1	CdLS	GSE12603	33056837	33057253	416

Validated miRNA targets

Micro RNA Name	Stem Loop Name	The chromosome that miRNA located	Publication
hsa-let-7b	hsa-let-7b	22	18668040
hsa-let-7b*	hsa-let-7b	22	18668040
hsa-miR-1	hsa-mir-1-2	18	18668040
hsa-miR-1	hsa-mir-1-1	20	18668040
hsa-miR-155	hsa-mir-155	21	18668040
hsa-miR-155*	hsa-mir-155	21	18668040
hsa-miR-16	hsa-mir-16-1	13	18668040
hsa-miR-16	hsa-mir-16-2	3	18668040
hsa-miR-30a	hsa-mir-30a	6	18668040
hsa-miR-30a*	hsa-mir-30a	6	18668040
hsa-miR-30b	hsa-mir-30b	8	18668040
hsa-miR-30b*	hsa-mir-30b	8	18668040
hsa-miR-30c	hsa-mir-30c-2	6	18668040
hsa-miR-30c	hsa-mir-30c-1	1	18668040
hsa-miR-30c-1*	hsa-mir-30c-1	1	18668040
hsa-miR-30c-2*	hsa-mir-30c-2	6	18668040
hsa-miR-30d	hsa-mir-30d	8	18668040
hsa-miR-30d*	hsa-mir-30d	8	18668040
hsa-miR-30e	hsa-mir-30e	1	18668040
hsa-miR-30e*	hsa-mir-30e	1	18668040

ID in Tarbase	Data Type	Support Type	miRNA	Gene	Direct Support	Publication
1255	Unknown	pSILAC	miR-30	NT5C3	down 50-25%	18668040
Ensembl	Protein Type	Differentially expressed in	Pathology or Event	Mis Regulation	Gene Expression	Tumour Involvement
ENSG00000122643		n_a	n_a	n_a	lymphocyte	"malignant tumour, carcinoma, leukaemia, sarcoma"

Cis-Nats regulation

Simple Query:

Paper Collected: 6/30/2018

Last Update: 8/26/2018