Annotation Detail for PCSK2
Basic Information Top
| Gene Symbol: | PCSK2 ( NEC2,PC2,SPC2 ) |
|---|---|
| Gene Full Name: | proprotein convertase subtilisin/kexin type 2 |
| Band: | 20p12.1 |
| Quick Links | Entrez ID:5126; OMIM: 162151; Uniprot ID:NEC2_HUMAN; ENSEMBL ID: ENSG00000125851; HGNC ID: 8744 |
| Relate to Another Database: | SFARIGene; denovo-db |
| Location(AA) | Modification | |
|---|---|---|
| 375 | N-linked (GlcNAc...) (Potential). | |
| 514 | N-linked (GlcNAc...) (Potential). | |
| 524 | N-linked (GlcNAc...) (Potential). | |
| Location(AA) | Modifications | Resource |
|---|---|---|
| 375 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 |
| 514 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 |
| 524 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 |
| Location(AA) | Modification | Resource |
|---|---|---|
| 82 | Phosphoserine(PKG) | HMM predict |
| 82 | Phosphoserine(PKA) | HMM predict |
| 111 | Phosphotyrosine(INSR) | HMM predict |
| 111 | Phosphotyrosine(EGFR) | HMM predict |
| 127 | Phosphothreonine(PKC) | HMM predict |
| 172 | Sulfotyrosine | HMM predict |
| 172 | Phosphotyrosine(Jak) | HMM predict |
| 349 | Phosphoserine(IKK) | HMM predict |
| 349 | Phosphoserine(CK1) | HMM predict |
| 350 | O-linked | HMM predict |
| 375 | N-linked | HMM predict |
| 514 | N-linked | HMM predict |
| 524 | N-linked | HMM predict |
- RefSeq ID: NM_002594
- Location:chr20 17155630-17413219
- strand:+
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| NRSF | Jurkat | GSE13047 | 17143836 | 17144094 | 258 | 11666 |
| NRSF | Jurkat | GSE13047 | 17154376 | 17156735 | 2359 | 75 |
| NRSF | Jurkat | SISSRdata | 17143836 | 17144063 | 227 | 11681 |
| NRSF | mAb | Jurkat | 17147500 | 17148595 | 1095 | 7583 |
| NRSF | mAb | Jurkat | 17151037 | 17151905 | 868 | 4160 |
| NRSF-mono | Jurkat | QuESTdata | 17143835 | 17144092 | 257 | 11667 |
| NRSF-poly | Jurkat | QuESTdata | 17143751 | 17144110 | 359 | 11700 |
| No data |
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| CTCF | CD4 | GSE12889 | 17360421 | 17360673 | 252 | 0 |
| CTCF | CD4 | SISSRdata | 17360421 | 17360673 | 252 | 0 |
| CTCF | Hela | GSE12889 | 17360429 | 17360710 | 281 | 0 |
| CTCF | Jurkat | GSE12889 | 17210207 | 17210404 | 197 | 0 |
| CTCF | G2 | GSE9613 | 17360419 | 17360795 | 376 | 0 |
| FOXA1 | MCF7 | GSE15244 | 17287174 | 17287948 | 774 | 0 |
| FOXA1 | MCF7 | GSE15244 | 17363727 | 17364665 | 938 | 0 |
| FOXA1 | eGFP | GSE10845 | 17287174 | 17287948 | 774 | 0 |
| FOXA1 | eGFP | GSE10845 | 17363727 | 17364665 | 938 | 0 |
| FoxA1 | MCF7 | MACSdata | 17162375 | 17162567 | 192 | 0 |
| FoxA1 | MCF7 | MACSdata | 17287615 | 17287792 | 177 | 0 |
| H3K27me3 | colorectal | cancer | 17155932 | 17157335 | 1403 | 0 |
| NRSF | mAb | Jurkat | 17152316 | 17159364 | 7048 | 0 |
| NRSF-mono | Jurkat | QuESTdata | 17154522 | 17156747 | 2225 | 0 |
| NRSF-mono | Jurkat | QuESTdata | 17368455 | 17368934 | 479 | 0 |
| NRSF-poly | Jurkat | QuESTdata | 17154549 | 17156735 | 2186 | 0 |
| NRSF-poly | Jurkat | QuESTdata | 17368455 | 17368959 | 504 | 0 |
| PAX3-FKHR | Rh4 | GSE19063 | 17286765 | 17288472 | 1707 | 0 |
| RARA | MCF7 | GSE15244 | 17286823 | 17287948 | 1125 | 0 |
| Rb | Growing | GSE19898 | 17272322 | 17272454 | 132 | 0 |
| Sox2 | hES | GSE18292 | 17371067 | 17371547 | 480 | 0 |
| TFAP2C | MCF7 | GSE21234 | 17287316 | 17288089 | 773 | 0 |
| hScc1 | Bcell | GSE12603 | 17360419 | 17360795 | 376 | 0 |
| hScc1 | Bcell | GSE12603 | 17396696 | 17396949 | 253 | 0 |
| hScc1 | Bcell | GSE12603 | 17400786 | 17401108 | 322 | 0 |
| hScc1 | Bcell | GSE12603 | 17402671 | 17403035 | 364 | 0 |
| hScc1 | CdLS | GSE12603 | 17360313 | 17360861 | 548 | 0 |
| hScc1 | G2 | GSE9613 | 17360200 | 17360795 | 595 | 0 |
| p63 | keratinocytes | GSE17611 | 17355980 | 17356890 | 910 | 0 |
Validated miRNA targets