AutismKB 2.0

Annotation Detail for GMPR2


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Basic Information Top
Gene Symbol:GMPR2 ( MGC15084,MGC830 )
Gene Full Name: guanosine monophosphate reductase 2
Band: 14q12
Quick LinksEntrez ID:51292; OMIM: 610781; Uniprot ID:GMPR2_HUMAN; ENSEMBL ID: ENSG00000100938; HGNC ID: 4377
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
13N6-acetyllysine.
291N6-acetyllysine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
23Phosphothreonine(PKA)HMM predict
23Phosphothreonine(PKC)HMM predict
37Phosphoserine(PKC)HMM predict
37Phosphoserine(CAMK2)HMM predict
37Phosphoserine(PKB)HMM predict
41Phosphoserine(PKG)HMM predict
45Phosphotyrosine(Syk)HMM predict
184Phosphoserine(IKK)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001002000
  • Location:chr14 23771487-23778284
  • strand:+
No data
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ETS1 JurkatGSE17954 23770696 23772560 1864 0
PHF8 293TGSE20725 23770696 23772355 1659 0
TFAP2C MCF7GSE21234 23770630 23772473 1843 0
USF1 HepG2E 23771040 23772197 1157 0
p130 QuiescentGSE19898 23771340 23771878 538 0
p130 shRbQuiescentGSE19898 23770878 23772603 1725 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018