AutismKB 2.0

Annotation Detail for TXNDC3


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Basic Information Top
Gene Symbol:TXNDC3 ( CILD6,NME8,SPTRX2 )
Gene Full Name: thioredoxin domain containing 3 (spermatozoa)
Band: 7p14.1
Quick LinksEntrez ID:51314; OMIM: 607421; Uniprot ID:TXND3_HUMAN; ENSEMBL ID: ENSG00000086288; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
16N-linkedHMM predict
143Phosphoserine(CK2)HMM predict
143Phosphoserine(CK1)HMM predict
237O-linkedHMM predict
237Phosphoserine(CK2)HMM predict
263Phosphothreonine(MAPK)HMM predict
377N-linkedHMM predict
506Phosphotyrosine(Syk)HMM predict
506Phosphotyrosine(EGFR)HMM predict
514Phosphoserine(ATM)HMM predict
548Phosphoserine(MAPK)HMM predict
572Phosphotyrosine(Syk)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_016616
  • Location:chr7 37854723-37906522
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 37839667 37840032 365 14874
CTCF CD4SISSRdata 37839667 37840032 365 14874
CTCF G2GSE9613 37839480 37840018 538 14975
ER Fulvestrant-MCF7GSE14664 37847878 37847910 32 6830
Oct1 HelaGSE14283 37845280 37845309 29 9429
Oct1 HelaGSE14283 37847765 37847837 72 6923
Oct1 HelaGSE14283 37847879 37847910 31 6829
hScc1 BcellGSE12603 37838387 37838632 245 16214
hScc1 BcellGSE12603 37839552 37840052 500 14922
hScc1 CdLSGSE12603 37838106 37838785 679 16278
hScc1 CdLSGSE12603 37839447 37840052 605 14974
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 37907468 37907777 309 1100
CTCF G2GSE9613 37908249 37908492 243 1848
Nanog hESGSE18292 37907508 37907744 236 1104
RARA MCF7GSE15244 37907705 37908565 860 1613
Sox2 hESGSE18292 37907493 37907741 248 1095
hScc1 BcellGSE12603 37907396 37907913 517 1132
hScc1 CdLSGSE12603 37907396 37908031 635 1191
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 37859743 37859952 209 0
Oct1 H2O2-HelaGSE14283 37875162 37875191 29 0
Oct1 HelaGSE14283 37875162 37875193 31 0
Oct1 HelaGSE14283 37904782 37904840 58 0
RNAII Tamoxifen-MCF7GSE14664 37898350 37898437 87 0
Stat6 IL-4-hr4GSE17850 37854730 37855255 525 0
hScc1 BcellGSE12603 37859558 37859952 394 0
hScc1 CdLSGSE12603 37859452 37859952 500 0
hScc1 G2GSE9613 37859671 37859952 281 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018