AutismKB 2.0

Annotation Detail for DACT1


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Basic Information Top
Gene Symbol:DACT1 ( DAPPER,DAPPER1,DPR1,FRODO,HDPR1,THYEX3 )
Gene Full Name: dapper, antagonist of beta-catenin, homolog 1 (Xenopus laevis)
Band: 14q23.1
Quick LinksEntrez ID:51339; OMIM: 607861; Uniprot ID:DACT1_HUMAN; ENSEMBL ID: ENSG00000165617; HGNC ID: 17748
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
836PDZ-binding (By similarity).
Location(AA) Modifications Resource
Location(AA) Modification Resource
8Phosphothreonine(PKC)HMM predict
44Phosphothreonine(PKC)HMM predict
74MethylarginineHMM predict
165Phosphoserine(ATM)HMM predict
169Phosphoserine(IKK)HMM predict
171Phosphoserine(IKK)HMM predict
173Phosphoserine(IKK)HMM predict
174N-linkedHMM predict
177N-linkedHMM predict
181O-linkedHMM predict
183S-palmitoylHMM predict
185Phosphoserine(CK1)HMM predict
187S-palmitoylHMM predict
235Phosphoserine(IKK)HMM predict
271Phosphoserine(CDC2)HMM predict
319Phosphoserine(IKK)HMM predict
319O-linkedHMM predict
322Phosphoserine(MAPK)HMM predict
322Phosphoserine(CDC2)HMM predict
324Phosphoserine(CK1)HMM predict
324O-linkedHMM predict
333O-linkedHMM predict
373N-linkedHMM predict
410N-linkedHMM predict
414Phosphoserine(CDC2)HMM predict
441Phosphoserine(IKK)HMM predict
460Phosphoserine(ATM)HMM predict
482Phosphoserine(IKK)HMM predict
485Phosphoserine(CDC2)HMM predict
489Phosphoserine(CDC2)HMM predict
489PhosphoserineHMM predict
491O-linkedHMM predict
522Phosphothreonine(MAPK)HMM predict
546Phosphoserine(ATM)HMM predict
600Phosphothreonine(PKC)HMM predict
609Phosphoserine(PKC)HMM predict
628Phosphoserine(PKC)HMM predict
656MethylarginineHMM predict
674Phosphothreonine(PKA)HMM predict
724O-linkedHMM predict
742Phosphoserine(CK2)HMM predict
747O-linkedHMM predict
748N-linkedHMM predict
752N-linkedHMM predict
760Phosphoserine(CK1)HMM predict
776O-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_016651
  • Location:chr14 58174611-58184788
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 58174207 58174815 608 101
H3K4me3 colorectalcancer 58173271 58174161 890 896
p130 shRbQuiescentGSE19898 58173591 58174287 696 673
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T0-glioblastomaGSE21026 58197321 58197529 208 12637
RARG MCF7GSE15244 58204267 58204960 693 19825
Rb QuiescentGSE19898 58200328 58200512 184 15632
TFAP2C MCF7GSE21234 58204223 58204800 577 19723
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Myc K562GSE19551 58182862 58183234 372 0
Oct1 HelaGSE14283 58179580 58179616 36 0
hScc1 BcellGSE12603 58174448 58175010 562 0
hScc1 BcellGSE12603 58176180 58176804 624 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018