AutismKB 2.0

Annotation Detail for PPME1


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Basic Information Top
Gene Symbol:PPME1 ( FLJ22226,PME-1 )
Gene Full Name: protein phosphatase methylesterase 1
Band: 11q13.4
Quick LinksEntrez ID:51400; OMIM: 611117; Uniprot ID:PPME1_HUMAN; ENSEMBL ID: ENSG00000214517; HGNC ID: 30178
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
6N6-acetyllysine.
15Phosphoserine.
27Phosphoserine (By similarity).
42Phosphoserine.
243Phosphoserine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
15Phosphoserine(PKA)HMM predict
15PhosphoserineHMM predict
22Phosphoserine(IKK)HMM predict
22O-linkedHMM predict
25Phosphoserine(ATM)HMM predict
37MethylarginineHMM predict
60N-linkedHMM predict
143Phosphotyrosine(EGFR)HMM predict
204Phosphothreonine(PKC)HMM predict
230Phosphoserine(PKG)HMM predict
230Phosphoserine(IKK)HMM predict
243Phosphoserine(CDC2)HMM predict
243Phosphoserine(MAPK)HMM predict
243Phosphoserine(CDK)HMM predict
247Phosphoserine(CK1)HMM predict
265Phosphoserine(CK1)HMM predict
372PhenylalanineHMM predict
373PhenylalanineHMM predict
375PhenylalanineHMM predict
386CysteineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_016147
  • Location:chr11 73560015-73643394
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
HIF1 HypoHepG2 73559520 73560448 928 32
PHF8 HeLaGSE20725 73559002 73560585 1583 222
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 73644447 73644886 439 1272
CTCF CD4SISSRdata 73644447 73644886 439 1272
TAFII hESGSE17917 73644514 73644762 248 1244
VDR GM10855-stimGSE22484 73643991 73645446 1455 1324
VDR GM10861-stimGSE22484 73643967 73645576 1609 1377
hScc1 BcellGSE12603 73644496 73644923 427 1315
hScc1 BcellGSE12603 73646619 73646825 206 3328
hScc1 CdLSGSE12603 73644496 73645014 518 1361
hScc1 G2GSE9613 73644496 73645303 807 1505
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
FOXA1 MCF7GSE15244 73559635 73560849 1214 0
GABP k562GSE8489 73559671 73561813 2142 0
H3K4me2 HCT116GSE10453 73560415 73561523 1108 0
H3K4me3 colorectalcancer 73560252 73561377 1125 0
H3ac HepG2E 73560147 73561960 1813 0
NRSF mAbJurkat 73560000 73561705 1705 0
NRSF pAbJurkat 73560000 73561341 1341 0
Nanog hESGSE18292 73638171 73638567 396 0
Oct1 H2O2-HelaGSE14283 73597115 73597166 51 0
Oct1 HelaGSE14283 73597115 73597166 51 0
RARG MCF7GSE15244 73559817 73560375 558 0
TAF HelaGSE8489 73560147 73561813 1666 0
TAF k562GSE8489 73559918 73561705 1787 0
hScc1 CdLSGSE12603 73559445 73560594 1149 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
4887 mRNA PME-1 chr11 73560015 73643395 66 EST chr11 73624493 73636603Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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