AutismKB 2.0

Annotation Detail for POLK


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Basic Information Top
Gene Symbol:POLK ( DINB1,DINP,POLQ )
Gene Full Name: polymerase (DNA directed) kappa
Band: 5q13.3
Quick LinksEntrez ID:51426; OMIM: 605650; Uniprot ID:POLK_HUMAN; ENSEMBL ID: ENSG00000122008; HGNC ID: 9183
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
372Phosphothreonine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
201Phosphotyrosine(Syk)HMM predict
203N-linkedHMM predict
258Phosphoserine(CK1)HMM predict
258Phosphoserine(ATM)HMM predict
310O-linkedHMM predict
355Phosphoserine(PKG)HMM predict
388Phosphoserine(CK1)HMM predict
415PhosphoserineHMM predict
423Phosphoserine(CAMK2)HMM predict
473Phosphothreonine(PKC)HMM predict
475O-linkedHMM predict
475O-linkedHMM predict
686Phosphotyrosine(Syk)HMM predict
686Phosphotyrosine(EGFR)HMM predict
709N-linkedHMM predict
730Phosphoserine(IKK)HMM predict
730Phosphoserine(CK1)HMM predict
744N-linkedHMM predict
763Phosphotyrosine(EGFR)HMM predict
788Phosphothreonine(CK2)HMM predict
803N-linkedHMM predict
827O-linkedHMM predict
827Phosphoserine(CK1)HMM predict
830O-linkedHMM predict
852Phosphothreonine(PKC)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_016218
  • Location:chr5 74843336-74930888
  • strand:+
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 74942934 74943288 354 12223
TFAP2C MCF7GSE21234 74933598 74934182 584 3002
p63 keratinocytesGSE17611 74934764 74935705 941 4346
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ER E2-MCF7GSE14664 74859781 74859829 48 0
ER E2-MCF7GSE14664 74930351 74930386 35 0
ER Fulvestrant-MCF7GSE14664 74859779 74859823 44 0
ER Fulvestrant-MCF7GSE14664 74862033 74862065 32 0
ER Fulvestrant-MCF7GSE14664 74930351 74930391 40 0
ETS1 JurkatGSE17954 74842686 74844174 1488 0
Fos K562GSE19551 74898335 74898912 577 0
Nanog ESGSE20650 74920333 74920681 348 0
Nanog hESGSE18292 74920398 74920744 346 0
Oct1 H2O2-HelaGSE14283 74896190 74896226 36 0
Oct1 H2O2-HelaGSE14283 74907381 74907414 33 0
Oct1 HelaGSE14283 74862032 74862070 38 0
Oct1 HelaGSE14283 74896188 74896228 40 0
RNAII Tamoxifen-MCF7GSE14664 74859780 74859822 42 0
Rb QuiescentGSE19898 74843367 74843835 468 0
Rb SenescentGSE19898 74842876 74843851 975 0
TFAP2C MCF7GSE21234 74868636 74868931 295 0
hScc1 CdLSGSE12603 74898422 74898628 206 0
p130 SenescentGSE19898 74842975 74843762 787 0
p130 shRbQuiescentGSE19898 74843242 74844139 897 0
p130 shRbSenescentGSE19898 74842853 74843858 1005 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
21131 mRNA POLK chr5 74843336 74930889 156 mRNA COL4A3BP chr5 74705735 74843719Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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