AutismKB 2.0

Annotation Detail for ANAPC7


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Basic Information Top
Gene Symbol:ANAPC7 ( APC7 )
Gene Full Name: anaphase promoting complex subunit 7
Band: 12q24.11
Quick LinksEntrez ID:51434; OMIM: 606949; Uniprot ID:APC7_HUMAN; ENSEMBL ID: ENSG00000196510; HGNC ID: 17380
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
85O-linkedHMM predict
91O-linkedHMM predict
92Phosphothreonine(CDK)HMM predict
92Phosphothreonine(CDC2)HMM predict
95Phosphoserine(IKK)HMM predict
154Phosphoserine(CK1)HMM predict
441Phosphotyrosine(INSR)HMM predict
471N-linkedHMM predict
499Phosphoserine(IKK)HMM predict
528PhosphothreonineHMM predict
548Phosphoserine(CK2)HMM predict
548Phosphoserine(CK1)HMM predict
550Phosphoserine(IKK)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_016238
  • Location:chr12 109296332-109325814
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ETS1 JurkatGSE17954 109325455 109326808 1353 317
Myc K562GSE19551 109325266 109326804 1538 221
p130 QuiescentGSE19898 109325680 109326298 618 175
p130 SenescentGSE19898 109325625 109326268 643 132
p130 shRbQuiescentGSE19898 109325634 109326746 1112 376
p130 shRbSenescentGSE19898 109325556 109326246 690 87
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T0-glioblastomaGSE21026 109290499 109291001 502 5583
p63 keratinocytesGSE17611 109292583 109293643 1060 3220
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Oct1 H2O2-HelaGSE14283 109311633 109311688 55 0
Oct1 HelaGSE14283 109311633 109311703 70 0
PHF8 HeLaGSE20725 109324875 109326638 1763 0
Rb QuiescentGSE19898 109325404 109326053 649 0
Rb SenescentGSE19898 109325545 109325955 410 0
Rb shRbSenescenceGSE19898 109325413 109325824 411 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018