AutismKB 2.0

Annotation Detail for LCMT1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:LCMT1 ( LCMT,PPMT1 )
Gene Full Name: leucine carboxyl methyltransferase 1
Band: 16p12.1
Quick LinksEntrez ID:51451; OMIM: 610286; Uniprot ID:LCMT1_HUMAN; ENSEMBL ID: ENSG00000205629; HGNC ID: 17557
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
181N6-acetyllysine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
9Phosphoserine(PKB)HMM predict
9Phosphoserine(IKK)HMM predict
12Phosphoserine(IKK)HMM predict
12O-linkedHMM predict
165Phosphotyrosine(INSR)HMM predict
165Phosphotyrosine(Syk)HMM predict
176Phosphoserine(CK2)HMM predict
260Phosphoserine(IKK)HMM predict
260Phosphoserine(CK1)HMM predict
263Phosphoserine(ATM)HMM predict
321ThreonineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001032391
  • Location:chr16 25030547-25097051
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 25025246 25025957 711 4946
CTCF G2GSE9613 25026807 25027241 434 3524
ER MCF7GSE19013 25019410 25019861 451 10912
ETS1 JurkatGSE17954 25029716 25030943 1227 218
Fos K562GSE19551 25030105 25030770 665 110
P300 T30-glioblastomaGSE21026 25016151 25017049 898 13948
P300 T30-glioblastomaGSE21026 25030005 25030987 982 52
PHF8 293TGSE20725 25025372 25026306 934 4709
PHF8 HeLaGSE20725 25025163 25026632 1469 4650
PHF8 Hs68minusFBSGSE20725 25025388 25026298 910 4705
PHF8 Hs68plusFBSGSE20725 25025151 25026510 1359 4717
Rb GrowingGSE19898 25030385 25030515 130 98
Rb QuiescentGSE19898 25030321 25030726 405 24
Rb SenescentGSE19898 25030387 25030675 288 17
TAF k562GSE8489 25028851 25029403 552 1421
hScc1 BcellGSE12603 25025173 25026141 968 4891
hScc1 CdLSGSE12603 25025103 25026077 974 4958
p130 QuiescentGSE19898 25030378 25030664 286 27
p130 SenescentGSE19898 25025759 25026369 610 4484
p130 SenescentGSE19898 25030200 25030758 558 69
p130 shRbQuiescentGSE19898 25029978 25030626 648 246
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 25045709 25045921 212 0
CTCF CD4SISSRdata 25045709 25045921 212 0
CTCF G2GSE9613 25056998 25057182 184 0
H3K4me3 colorectalcancer 25030940 25031463 523 0
H3ac HepG2E 25030940 25031661 721 0
P300 T30-glioblastomaGSE21026 25070490 25071606 1116 0
RARA MCF7GSE15244 25037459 25038674 1215 0
RARA MCF7GSE15244 25096407 25096815 408 0
STAT1 IFNSISSRdata 25045448 25046162 714 0
Stat6 IL-4-hr4GSE17850 25036816 25037303 487 0
TFAP2C MCF7GSE21234 25038071 25038864 793 0
p130 shRbSenescentGSE19898 25030290 25030881 591 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
9765 mRNA LCMT1 chr16 25030595 25097050 8456 mRNA chr16 25059398 25067854 Non-exonic Bidirectional (NOB) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018