Annotation Detail for ANKFY1

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Basic Information Top

Gene Symbol:	ANKFY1 ( ANKHZN,DKFZp686M19106,KIAA1255,ZFYVE14 )
Gene Full Name:	ankyrin repeat and FYVE domain containing 1
Band:	17p13.2
Quick Links	Entrez ID:51479; OMIM: 607927; Uniprot ID:ANFY1_HUMAN; ENSEMBL ID: ENSG00000185722; HGNC ID: 20763
Relate to Another Database:	SFARIGene; denovo-db

Post Translation Modification

Location(AA)	Modification
2	N-acetylalanine.

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
P300	T0-glioblastoma	GSE21026	4011048	4011970	922	1907
P300	T30-glioblastoma	GSE21026	4010855	4013332	2477	1322
RARA	MCF7	GSE15244	4010987	4012142	1155	1851
RARG	MCF7	GSE15244	4011024	4012142	1118	1833
TFAP2C	MCF7	GSE21234	4011114	4013227	2113	1245

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length
CTCF	G2	GSE9613	4038022	4038311	289
CTCF	G2	GSE9613	4039530	4040018	488
GABP	Hela	GSE8489	4041209	4042659	1450
RARA	MCF7	GSE15244	4041209	4042768	1559
RARG	MCF7	GSE15244	4028336	4028823	487
RARG	MCF7	GSE15244	4037241	4037668	427
RARG	MCF7	GSE15244	4041209	4042768	1559
p63	keratinocytes	GSE17611	4037027	4037889	862

Validated miRNA targets

Micro RNA Name	Stem Loop Name	The chromosome that miRNA located	Publication
hsa-let-7b	hsa-let-7b	22	18668040
hsa-let-7b*	hsa-let-7b	22	18668040
hsa-miR-1	hsa-mir-1-2	18	18668040
hsa-miR-1	hsa-mir-1-1	20	18668040
hsa-miR-155	hsa-mir-155	21	18668040
hsa-miR-155*	hsa-mir-155	21	18668040
hsa-miR-16	hsa-mir-16-1	13	18668040
hsa-miR-16	hsa-mir-16-2	3	18668040
hsa-miR-30a	hsa-mir-30a	6	18668040
hsa-miR-30a*	hsa-mir-30a	6	18668040
hsa-miR-30b	hsa-mir-30b	8	18668040
hsa-miR-30b*	hsa-mir-30b	8	18668040
hsa-miR-30c	hsa-mir-30c-2	6	18668040
hsa-miR-30c	hsa-mir-30c-1	1	18668040
hsa-miR-30c-1*	hsa-mir-30c-1	1	18668040
hsa-miR-30c-2*	hsa-mir-30c-2	6	18668040
hsa-miR-30d	hsa-mir-30d	8	18668040
hsa-miR-30d*	hsa-mir-30d	8	18668040
hsa-miR-30e	hsa-mir-30e	1	18668040
hsa-miR-30e*	hsa-mir-30e	1	18668040

ID in Tarbase	Data Type	Support Type	miRNA	Gene	Direct Support	Publication
934	Unknown	pSILAC	miR-155	ANKFY1	down 75-50%	18668040
Ensembl	Protein Type	Differentially expressed in	Pathology or Event	Mis Regulation	Gene Expression	Tumour Involvement
ENSG00000185722		n_a	n_a	n_a	"epithelium, lymphocyte, macrophage, muscle cell"	"benign tumour, malignant tumour, carcinoma, leukaemia, sarcoma"

Cis-Nats regulation

Cluster ID	Plue Type	Plus Gene Name	Plus Chromosome	Plus Start	Plus End	Overlap Length	Minus Type	Minus Gene Name	Minus Chromosome	Minus Star	Minus End	Type
10504	EST		chr17	3999950	4033705	154	mRNA	ANKFY1	chr17	4013949	4114000	Sense/Antisense (SA) pairs

Simple Query:

Paper Collected: 6/30/2018

Last Update: 8/26/2018