Annotation Detail for PTPLAD1

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Basic Information Top

Gene Symbol:	PTPLAD1 ( B-IND1,FLJ90376,HACD3,HSPC121 )
Gene Full Name:	protein tyrosine phosphatase-like A domain containing 1
Band:	15q22.2
Quick Links	Entrez ID:51495; OMIM: NA; Uniprot ID:HACD3_HUMAN; ENSEMBL ID: ENSG00000074696; HGNC ID:
Relate to Another Database:	SFARIGene; denovo-db

Post Translation Modification

Location(AA)	Modification
114	Phosphoserine.

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
H3ac	HepG2	E	63609383	63609593	210	392

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length
FOXA1	MCF7	GSE15244	63613685	63614009	324
FOXA1	eGFP	GSE10845	63613685	63614009	324
H3ac	HepG2	E	63610685	63610917	232
PHF8	293T	GSE20725	63609397	63610938	1541
PHF8	HeLa	GSE20725	63609232	63610990	1758
Rb	Senescent	GSE19898	63609908	63610134	226
TFAP2C	MCF7	GSE21234	63640961	63641782	821
hScc1	CdLS	GSE12603	63609490	63610339	849
p130	Senescent	GSE19898	63609902	63610592	690

Validated miRNA targets

Micro RNA Name	Stem Loop Name	The chromosome that miRNA located	Publication
hsa-let-7b	hsa-let-7b	22	18668040
hsa-let-7b*	hsa-let-7b	22	18668040
hsa-miR-1	hsa-mir-1-2	18	18668040
hsa-miR-1	hsa-mir-1-1	20	18668040
hsa-miR-155	hsa-mir-155	21	18668040
hsa-miR-155*	hsa-mir-155	21	18668040
hsa-miR-16	hsa-mir-16-1	13	18668040
hsa-miR-16	hsa-mir-16-2	3	18668040
hsa-miR-30a	hsa-mir-30a	6	18668040
hsa-miR-30a*	hsa-mir-30a	6	18668040
hsa-miR-30b	hsa-mir-30b	8	18668040
hsa-miR-30b*	hsa-mir-30b	8	18668040
hsa-miR-30c	hsa-mir-30c-2	6	18668040
hsa-miR-30c	hsa-mir-30c-1	1	18668040
hsa-miR-30c-1*	hsa-mir-30c-1	1	18668040
hsa-miR-30c-2*	hsa-mir-30c-2	6	18668040
hsa-miR-30d	hsa-mir-30d	8	18668040
hsa-miR-30d*	hsa-mir-30d	8	18668040
hsa-miR-30e	hsa-mir-30e	1	18668040
hsa-miR-30e*	hsa-mir-30e	1	18668040

ID in Tarbase	Data Type	Support Type	miRNA	Gene	Direct Support	Publication
1188	Unknown	pSILAC	miR-1	PTPLAD1	down 50-25%	18668040
Ensembl	Protein Type	Differentially expressed in	Pathology or Event	Mis Regulation	Gene Expression	Tumour Involvement
ENSG00000074696		n_a	n_a	n_a	"epithelium, lymphoblast, lymphocyte, muscle cell"	"benign tumour, malignant tumour, carcinoma, leukaemia, sarcoma"

Cis-Nats regulation

Simple Query:

Paper Collected: 6/30/2018

Last Update: 8/26/2018