AutismKB 2.0

Annotation Detail for PDE8A


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Basic Information Top
Gene Symbol:PDE8A ( FLJ16150,HsT19550 )
Gene Full Name: phosphodiesterase 8A
Band: 15q25.3
Quick LinksEntrez ID:5151; OMIM: 602972; Uniprot ID:PDE8A_HUMAN; ENSEMBL ID: ENSG00000073417; HGNC ID: 8793
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
20Phosphoserine.
386Phosphoserine.
407Phosphoserine.
457Phosphoserine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
20Phosphoserine(CDC2)HMM predict
20Phosphoserine(MAPK)HMM predict
20Phosphoserine(IKK)HMM predict
20Phosphoserine(CDK)HMM predict
20O-linkedHMM predict
27O-linkedHMM predict
153Phosphoserine(CK1)HMM predict
347N-linkedHMM predict
359Phosphoserine(PKG)HMM predict
380Phosphoserine(PKB)HMM predict
407O-linkedHMM predict
457Phosphoserine(PKC)HMM predict
457Phosphoserine(PKG)HMM predict
457Phosphoserine(PKA)HMM predict
497Phosphotyrosine(Syk)HMM predict
555Phosphotyrosine(Jak)HMM predict
557N-linkedHMM predict
620N-linkedHMM predict
710Phosphothreonine(MAPK)HMM predict
713N-linkedHMM predict
750Phosphoserine(ATM)HMM predict
780Phosphoserine(CK2)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_002605
  • Location:chr15 83326208-83483373
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 83324700 83326537 1837 590
H3K4me3 colorectalcancer 83325733 83326615 882 35
Oct1 HelaGSE14283 83324490 83324560 70 1684
PHF8 HeLaGSE20725 83324420 83327207 2787 395
PHF8 Hs68plusFBSGSE20725 83324470 83327100 2630 424
hScc1 BcellGSE12603 83324801 83326820 2019 398
p130 QuiescentGSE19898 83325092 83325534 442 896
p130 SenescentGSE19898 83324607 83325514 907 1148
p130 shRbQuiescentGSE19898 83325188 83325526 338 852
p130 shRbSenescentGSE19898 83325045 83325707 662 833
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Oct1 HelaGSE14283 83486250 83486278 28 2891
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T30-glioblastomaGSE21026 83391084 83392447 1363 0
CTCF CD4GSE12889 83388479 83388823 344 0
CTCF CD4SISSRdata 83388479 83388823 344 0
CTCF G2GSE9613 83388498 83389002 504 0
FOXA1 MCF7GSE15244 83391553 83392138 585 0
FOXA1 MCF7GSE15244 83424438 83425475 1037 0
FOXA1 eGFPGSE10845 83391553 83392138 585 0
FOXA1 eGFPGSE10845 83424438 83425475 1037 0
Fos K562GSE19551 83336730 83337231 501 0
FoxA1 MCF7MACSdata 83391890 83392169 279 0
FoxA1 MCF7MACSdata 83424624 83424867 243 0
H3K4me3 colorectalcancer 83327797 83327967 170 0
H3ac HepG2E 83327323 83328118 795 0
H3ac HepG2E 83328678 83328937 259 0
NFkBII GM12878GSE19485 83346291 83347719 1428 0
Oct1 H2O2-HelaGSE14283 83331439 83331467 28 0
Oct1 H2O2-HelaGSE14283 83424773 83424803 30 0
Oct1 H2O2-HelaGSE14283 83426215 83426246 31 0
Oct1 H2O2-HelaGSE14283 83438385 83438414 29 0
Oct1 HelaGSE14283 83379389 83379424 35 0
Oct1 HelaGSE14283 83379680 83379709 29 0
Oct1 HelaGSE14283 83382484 83382528 44 0
Oct1 HelaGSE14283 83400259 83400311 52 0
Oct1 HelaGSE14283 83424773 83424803 30 0
Oct1 HelaGSE14283 83426214 83426254 40 0
P300 T30-glioblastomaGSE21026 83336422 83337321 899 0
P300 T30-glioblastomaGSE21026 83391223 83392144 921 0
Sox2 hESGSE18292 83364216 83364618 402 0
TFAP2C MCF7GSE21234 83391503 83392148 645 0
TFAP2C MCF7GSE21234 83424492 83425059 567 0
TFAP2C MCF7GSE21234 83460158 83460647 489 0
hScc1 BcellGSE12603 83388275 83388965 690 0
hScc1 CdLSGSE12603 83388233 83388929 696 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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