AutismKB 2.0

Annotation Detail for PDE1B


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Basic Information Top
Gene Symbol:PDE1B ( PDE1B1,PDES1B )
Gene Full Name: phosphodiesterase 1B, calmodulin-dependent
Band: 12q13.2
Quick LinksEntrez ID:5153; OMIM: 171891; Uniprot ID:PDE1B_HUMAN; ENSEMBL ID: ENSG00000123360; HGNC ID: 8775
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
466Phosphoserine (By similarity).
Location(AA) Modifications Resource
466Phosphoserine (By similarity).Swiss-Prot 53.0
Location(AA) Modification Resource
7Phosphoserine(ATM)HMM predict
7Phosphoserine(IKK)HMM predict
7Phosphoserine(CDC2)HMM predict
19Phosphoserine(IKK)HMM predict
81Phosphothreonine(CK2)HMM predict
144Phosphothreonine(PKA)HMM predict
145O-linkedHMM predict
149O-linkedHMM predict
150Phosphotyrosine(Abl)HMM predict
265SulfotyrosineHMM predict
314N-linkedHMM predict
452Phosphoserine(CK1)HMM predict
454Phosphoserine(IKK)HMM predict
454Phosphoserine(CK1)HMM predict
502Phosphoserine(PKG)HMM predict
523Phosphoserine(MAPK)HMM predict
523Phosphoserine(IKK)HMM predict
523PhosphoserineHMM predict
523O-linkedHMM predict
523Phosphoserine(ATM)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_000924
  • Location:chr12 53229670-53259289
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 53229100 53229497 397 372
H3K27me3 colorectalcancer 53227587 53228121 534 1817
H3K27me3 colorectalcancer 53229062 53229364 302 458
NRSF pAbJurkat 53229167 53229811 644 182
Rb GrowingGSE19898 53226481 53226635 154 3113
VDR GM10861-stimGSE22484 53226210 53230507 4297 1312
hScc1 BcellGSE12603 53229062 53229497 435 391
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 53238202 53238710 508 0
CTCF G2GSE9613 53241394 53241724 330 0
CTCF G2GSE9613 53245117 53245374 257 0
CTCF G2GSE9613 53249123 53249482 359 0
CTCF G2GSE9613 53252790 53253419 629 0
FOXA1 MCF7GSE15244 53229062 53230425 1363 0
FOXA1 MCF7GSE15244 53243036 53243417 381 0
Fos K562GSE19551 53240292 53240988 696 0
H3K27me3 colorectalcancer 53230020 53231523 1503 0
NRSF pAbJurkat 53249084 53249444 360 0
NRSF pAbJurkat 53252971 53253178 207 0
Nanog hESGSE18292 53244735 53245413 678 0
Oct1 HelaGSE14283 53234444 53234473 29 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
6093 mRNA PDE1B chr12 53229670 53259290 443 mRNA chr12 53255437 53268723Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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