AutismKB 2.0

Annotation Detail for ZC3HC1


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Basic Information Top
Gene Symbol:ZC3HC1 ( 1110054L24Rik,FBXO50,NIPA )
Gene Full Name: zinc finger, C3HC-type containing 1
Band: 7q32.2
Quick LinksEntrez ID:51530; OMIM: NA; Uniprot ID:NIPA_HUMAN; ENSEMBL ID: ENSG00000091732; HGNC ID: 29913
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
2N-acetylalanine.
24Phosphoserine.
28Phosphothreonine.
58Phosphoserine.
62Phosphoserine.
84Phosphothreonine.
321Phosphoserine.
333Phosphothreonine.
335Phosphoserine.
338Phosphoserine.
344Phosphoserine.
354Phosphoserine.
357Phosphoserine.
359Phosphoserine.
370Phosphoserine.
384Phosphothreonine.
387Phosphothreonine.
394Phosphoserine.
395Phosphoserine.
402Nuclear localization signal.
Location(AA) Modifications Resource
24Phosphoserine.Swiss-Prot 53.0
24PhosphoserinePhospho.ELM 6.0
28Phosphothreonine.Swiss-Prot 53.0
28PhosphothreoninePhospho.ELM 6.0
62Phosphoserine (By similarity).Swiss-Prot 53.0
62PhosphoserinePhospho.ELM 6.0
105Phosphotyrosine (ALK)Phospho.ELM 6.0
137Phosphotyrosine (ALK)Phospho.ELM 6.0
321Phosphoserine.Swiss-Prot 53.0
321PhosphoserinePhospho.ELM 6.0
354PhosphoserinePhospho.ELM 6.0
354Phosphoserine.Swiss-Prot 53.0
370Phosphoserine (By similarity).Swiss-Prot 53.0
Location(AA) Modification Resource
24Phosphoserine(CDC2)HMM predict
53Phosphoserine(IKK)HMM predict
56Phosphoserine(ATM)HMM predict
58Phosphoserine(IKK)HMM predict
60N-linkedHMM predict
62Phosphoserine(CDC2)HMM predict
69Phosphoserine(IKK)HMM predict
73Phosphothreonine(CK2)HMM predict
161Phosphoserine(CDC2)HMM predict
254S-palmitoylHMM predict
301O-linkedHMM predict
303Phosphoserine(CDC2)HMM predict
321Phosphoserine(CDC2)HMM predict
327Phosphothreonine(PKA)HMM predict
329Phosphoserine(ATM)HMM predict
335Phosphoserine(MAPK)HMM predict
338Phosphoserine(CK2)HMM predict
354Phosphoserine(PKA)HMM predict
354Phosphoserine(PKB)HMM predict
354Phosphoserine(IKK)HMM predict
354Phosphoserine(CAMK2)HMM predict
370O-linkedHMM predict
370Phosphoserine(CDC2)HMM predict
372Phosphothreonine(PKC)HMM predict
387Phosphothreonine(MAPK)HMM predict
395Phosphoserine(CDC2)HMM predict
395Phosphoserine(CDK)HMM predict
413O-linkedHMM predict
423Phosphoserine(ATM)HMM predict
433N-linkedHMM predict
440Phosphoserine(PKG)HMM predict
472Phosphoserine(ATM)HMM predict
479Phosphoserine(IKK)HMM predict
481Phosphoserine(CK1)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_016478
  • Location:chr7 129445361-129478468
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
TFAP2C MCF7GSE21234 129478170 129478776 606 5
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 129437976 129438221 245 7263
CTCF CD4SISSRdata 129437976 129438221 245 7263
CTCF HelaGSE12889 129438005 129438175 170 7272
CTCF JurkatGSE12889 129437938 129438289 351 7248
CTCF G2GSE9613 129437523 129438139 616 7531
Nanog hESGSE18292 129437955 129438204 249 7282
TAFII hESGSE17917 129438010 129438313 303 7200
hScc1 BcellGSE12603 129437624 129438139 515 7480
hScc1 CdLSGSE12603 129437523 129438139 616 7531
hScc1 G2GSE9613 129437523 129438139 616 7531
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ETS1 JurkatGSE17954 129477886 129478880 994 0
Fos K562GSE19551 129452903 129453600 697 0
GABP k562GSE8489 129475978 129476600 622 0
GABP k562GSE8489 129478031 129478700 669 0
H3K4me3 colorectalcancer 129478031 129478330 299 0
H3ac HepG2E 129478031 129478440 409 0
Myc K562GSE19551 129452886 129453536 650 0
Myc K562GSE19551 129478062 129478830 768 0
P300 T0-glioblastomaGSE21026 129477682 129478755 1073 0
P300 T30-glioblastomaGSE21026 129452718 129453707 989 0
P300 T30-glioblastomaGSE21026 129478068 129478821 753 0
PolII HeLaGSE12783 129477825 129478871 1046 0
STAT1 HeLaGSE12783 129452612 129453746 1134 0
STAT1 IFNSISSRdata 129452884 129453604 720 0
TAF HelaGSE8489 129476929 129477115 186 0
TAF HelaGSE8489 129478031 129478330 299 0
TAF k562GSE8489 129475978 129476600 622 0
TAF k562GSE8489 129478031 129478700 669 0
TAFII hESGSE17917 129478028 129478681 653 0
TFAP2C MCF7GSE21234 129453017 129453390 373 0
p130 QuiescentGSE19898 129478130 129478731 601 0
p130 SenescentGSE19898 129478140 129478703 563 0
p130 shRbQuiescentGSE19898 129477912 129478748 836 0
p130 shRbSenescentGSE19898 129478106 129478731 625 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018