Annotation Detail for SIRT6
Basic Information Top
| Gene Symbol: | SIRT6 ( SIR2L6 ) |
|---|---|
| Gene Full Name: | sirtuin 6 |
| Band: | 19p13.3 |
| Quick Links | Entrez ID:51548; OMIM: 606211; Uniprot ID:SIRT6_HUMAN; ENSEMBL ID: ENSG00000077463; HGNC ID: 14934 |
| Relate to Another Database: | SFARIGene; denovo-db |
| Location(AA) | Modification | |
|---|---|---|
| 10 | Phosphoserine. | |
| 294 | Phosphothreonine. | |
| 303 | Phosphoserine. | |
| Location(AA) | Modifications | Resource |
|---|
| Location(AA) | Modification | Resource |
|---|---|---|
| 112 | Phosphoserine(ATM) | HMM predict |
| 294 | Phosphothreonine(CDK) | HMM predict |
| 294 | Phosphothreonine(MAPK) | HMM predict |
| 294 | Phosphothreonine | HMM predict |
| 308 | N-linked | HMM predict |
| 324 | N-linked | HMM predict |
| 326 | O-linked | HMM predict |
| 330 | Phosphoserine | HMM predict |
| 330 | Phosphoserine(CDC2) | HMM predict |
| 330 | Phosphoserine(CDK) | HMM predict |
| 330 | Phosphoserine(MAPK) | HMM predict |
| 337 | Phosphothreonine(PKA) | HMM predict |
| 338 | Phosphoserine(ATM) | HMM predict |
| 338 | Phosphoserine(MAPK) | HMM predict |
| 338 | Phosphoserine | HMM predict |
| 338 | O-linked | HMM predict |
| 338 | Phosphoserine(CDC2) | HMM predict |
| 338 | Phosphoserine(IKK) | HMM predict |
- RefSeq ID: NM_016539
- Location:chr19 4125106-4133595
- strand:-
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| CTCF | CD4 | GSE12889 | 4137436 | 4137733 | 297 | 3989 |
| CTCF | CD4 | SISSRdata | 4137436 | 4137733 | 297 | 3989 |
| CTCF | G2 | GSE9613 | 4136923 | 4137905 | 982 | 3819 |
| GABP | k562 | GSE8489 | 4133474 | 4133937 | 463 | 110 |
| H3K27me3 | colorectal | cancer | 4149665 | 4150213 | 548 | 16344 |
| H3K27me3 | colorectal | cancer | 4152013 | 4152571 | 558 | 18697 |
| H3ac | HepG2 | E | 4133722 | 4133937 | 215 | 234 |
| TAF | Hela | GSE8489 | 4151826 | 4152535 | 709 | 18585 |
| TAF | k562 | GSE8489 | 4151826 | 4152368 | 542 | 18502 |
| TFAP2C | MCF7 | GSE21234 | 4133507 | 4134103 | 596 | 210 |
| hScc1 | Bcell | GSE12603 | 4135172 | 4135400 | 228 | 1691 |
| hScc1 | Bcell | GSE12603 | 4137032 | 4137797 | 765 | 3819 |
| hScc1 | CdLS | GSE12603 | 4137294 | 4137871 | 577 | 3987 |
| hScc1 | G2 | GSE9613 | 4136923 | 4137871 | 948 | 3802 |
| No data |
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| ETS1 | Jurkat | GSE17954 | 4130957 | 4131882 | 925 | 0 |
| ETS1 | Jurkat | GSE17954 | 4133050 | 4133975 | 925 | 0 |
| Fos | K562 | GSE19551 | 4131210 | 4131639 | 429 | 0 |
| GABP | k562 | GSE8489 | 4133025 | 4133232 | 207 | 0 |
| H3ac | HepG2 | E | 4133025 | 4133347 | 322 | 0 |
| NRSF | Jurkat | GSE13047 | 4125013 | 4125674 | 661 | 0 |
| NRSF | Jurkat | GSE13047 | 4125677 | 4127269 | 1592 | 0 |
| NRSF | mAb | Jurkat | 4127032 | 4127263 | 231 | 0 |
| NRSF | mAb | Jurkat | 4128032 | 4128524 | 492 | 0 |
| NRSF | mAb | Jurkat | 4129864 | 4131065 | 1201 | 0 |
| PHF8 | 293T | GSE20725 | 4132931 | 4134069 | 1138 | 0 |
| Rb | shRbSenescence | GSE19898 | 4133054 | 4133283 | 229 | 0 |
| USF1 | HepG2 | E | 4129864 | 4131065 | 1201 | 0 |
| USF1 | HepG2 | E | 4131621 | 4132405 | 784 | 0 |
| USF1 | HepG2 | E | 4133025 | 4133382 | 357 | 0 |
| hScc1 | Bcell | GSE12603 | 4126147 | 4127032 | 885 | 0 |
| hScc1 | Bcell | GSE12603 | 4131621 | 4132020 | 399 | 0 |
| p130 | Senescent | GSE19898 | 4132894 | 4133331 | 437 | 0 |
| p130 | shRbQuiescent | GSE19898 | 4132944 | 4133716 | 772 | 0 |
Validated miRNA targets