AutismKB 2.0

Annotation Detail for PDGFB


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Basic Information Top
Gene Symbol:PDGFB ( FLJ12858,PDGF2,SIS,SSV,c-sis )
Gene Full Name: platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)
Band: 22q13.1
Quick LinksEntrez ID:5155; OMIM: 190040; Uniprot ID:PDGFB_HUMAN; ENSEMBL ID: ENSG00000100311; HGNC ID: 8800
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
12S-palmitoylHMM predict
13S-palmitoylHMM predict
30PhosphotyrosineHMM predict
30Phosphotyrosine(Syk)HMM predict
63N-linkedHMM predict
69Phosphoserine(CAMK2)HMM predict
82Phosphoserine(PKG)HMM predict
133S-palmitoylHMM predict
134S-palmitoylHMM predict
192Phosphoserine(IKK)HMM predict
192Phosphoserine(CDC2)HMM predict
196Phosphoserine(ATM)HMM predict
203Phosphothreonine(CDK)HMM predict
209Phosphothreonine(PKA)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_002608
  • Location:chr22 37949664-37970935
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
FOXA1 MCF7GSE15244 37977936 37978906 970 7486
Fos K562GSE19551 37979381 37979864 483 8687
NFkBII GM12878GSE19485 37980359 37981836 1477 10162
P300 T30-glioblastomaGSE21026 37977526 37980092 2566 7874
STAT1 HeLaGSE12782 37989373 37990761 1388 19132
STAT1 HeLaGSE12783 37989407 37990657 1250 19097
TFAP2C MCF7GSE21234 37977925 37978432 507 7243
hScc1 BcellGSE12603 37980553 37981190 637 9936
hScc1 BcellGSE12603 37984867 37985088 221 14042
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 37967916 37968745 829 0
PolII HeLaGSE12783 37968490 37971624 3134 0
TFAP2C MCF7GSE21234 37966599 37967742 1143 0
USF1 HepG2E 37965902 37967916 2014 0
USF2 HepG2E 37966530 37967702 1172 0
hScc1 BcellGSE12603 37967044 37967363 319 0
hScc1 BcellGSE12603 37968195 37969317 1122 0
hScc1 BcellGSE12603 37969664 37970202 538 0
hScc1 CdLSGSE12603 37967546 37969506 1960 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-126 hsa-mir-126 9 19917099
hsa-miR-126* hsa-mir-126 9 19917099
hsa-miR-145 hsa-mir-145 5 19917099
hsa-miR-145* hsa-mir-145 5 19917099
hsa-miR-23a hsa-mir-23a 19 19917099
hsa-miR-23a* hsa-mir-23a 19 19917099
hsa-miR-24 hsa-mir-24-1 9 20019669
hsa-miR-24 hsa-mir-24-2 19 20019669
hsa-miR-24 hsa-mir-24-1 9 19917099
hsa-miR-24 hsa-mir-24-2 19 19917099
hsa-miR-24-1* hsa-mir-24-1 9 20019669
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018