Annotation Detail for GDE1

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Basic Information Top

Gene Symbol:	GDE1 ( 363E6.2,MIR16 )
Gene Full Name:	glycerophosphodiester phosphodiesterase 1
Band:	16p12.3
Quick Links	Entrez ID:51573; OMIM: 605943; Uniprot ID:GDE1_HUMAN; ENSEMBL ID: ENSG00000006007; HGNC ID: 29644
Relate to Another Database:	SFARIGene; denovo-db

Pathways, Diseases and Drugs

TF binding site

Post Translation Modification

PTM Sites from Uniprot:2 results
Experimental PTM Sites from dbPTM:2 results
Predicted PTM Sites by profile HMM from dbPTM:7 results

Location(AA)	Modification
168	N-linked (GlcNAc...) (Potential).
198	N-linked (GlcNAc...) (Potential).

Location(AA)	Modification	Resource
27	Phosphoserine(CDC2)	HMM predict
27	Phosphoserine(CDK)	HMM predict
156	Phosphothreonine(PKC)	HMM predict
168	N-linked	HMM predict
183	Phosphothreonine(PKA)	HMM predict
230	Phosphoserine(IKK)	HMM predict
310	Phosphotyrosine(EGFR)	HMM predict

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

RefSeq ID: NM_016641
Location:chr16 19420517-19440950
strand:-

Upstream the gene:1 results
Downstream the gene:0 results
Inside the gene:14 results

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
H3ac	HepG2	E	19441112	19441361	249	286

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CTCF	CD4	GSE12889	19421521	19421772	251	0
CTCF	CD4	SISSRdata	19421521	19421772	251	0
CTCF	G2	GSE9613	19421604	19422091	487	0
CTCF	G2	GSE9613	19440405	19441039	634	0
FOXA1	MCF7	GSE15244	19435778	19436670	892	0
H3K4me3	colorectal	cancer	19438860	19439036	176	0
H3K4me3	colorectal	cancer	19439572	19440405	833	0
H3ac	HepG2	E	19439572	19440405	833	0
PHF8	293T	GSE20725	19440366	19441355	989	0
PHF8	HeLa	GSE20725	19440369	19441425	1056	0
TAF	Hela	GSE8489	19439572	19440650	1078	0
hScc1	Bcell	GSE12603	19421604	19421913	309	0
hScc1	Bcell	GSE12603	19440686	19440936	250	0
hScc1	CdLS	GSE12603	19421604	19421878	274	0

Validated miRNA targets

miR Walk:5 results
Tarbase V5.0:0 results

Micro RNA Name	Stem Loop Name	The chromosome that miRNA located	Publication
hsa-miR-15a	hsa-mir-15a	13	20031211
hsa-miR-15a*	hsa-mir-15a	13	20031211
hsa-miR-16	hsa-mir-16-1	13	20031211
hsa-miR-16	hsa-mir-16-2	3	20031211
hsa-miR-16-1*	hsa-mir-16-1	13	20031211

Cis-Nats regulation

Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

Studies: 1,036
Genes: 1,379
CNVs/SVs: 5,420
SNVs/Indels: 11,669
de novo Mutations: 5,669
Mosaics: 789
Linkage Regions: 172

Paper Collected: 6/30/2018

Last Update: 8/26/2018

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