AutismKB 2.0

Annotation Detail for MED15


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:MED15 ( ARC105,CAG7A,CTG7A,DKFZp686A2214,DKFZp762B1216,FLJ42282,FLJ42935,PCQAP,TIG-1,TIG1,TNRC7 )
Gene Full Name: mediator complex subunit 15
Band: 22q11.21
Quick LinksEntrez ID:51586; OMIM: 607372; Uniprot ID:MED15_HUMAN; ENSEMBL ID: ENSG00000099917; HGNC ID: 14248
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
1N-acetylmethionine.
564Nuclear localization signal (Potential).
603Phosphothreonine.
Location(AA) Modifications Resource
No data
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001003891
  • Location:chr22 19191885-19271917
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
GABP k562GSE8489 19190820 19192653 1833 149
H3ac HepG2E 19190820 19192653 1833 149
Oct4 hESGSE17917 19191769 19191985 216 9
VDR GM10861-UnstimGSE22484 19191171 19192522 1351 39
hScc1 BcellGSE12603 19191551 19191882 331 169
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 19290566 19290776 210 18754
CTCF CD4SISSRdata 19290566 19290776 210 18754
CTCF HelaGSE12889 19290581 19290905 324 18826
CTCF JurkatGSE12889 19290577 19290792 215 18767
TFAP2C MCF7GSE21234 19291400 19292043 643 19804
hScc1 BcellGSE12603 19272069 19272601 532 418
hScc1 BcellGSE12603 19273795 19274408 613 2184
hScc1 BcellGSE12603 19286976 19287409 433 15275
hScc1 BcellGSE12603 19289275 19289907 632 17674
hScc1 BcellGSE12603 19290357 19291384 1027 18953
hScc1 CdLSGSE12603 19290319 19291166 847 18825
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF HelaGSE12889 19248626 19248949 323 0
CTCF G2GSE9613 19236637 19236937 300 0
CTCF G2GSE9613 19248477 19249026 549 0
CTCF G2GSE9613 19255501 19256229 728 0
CTCF G2GSE9613 19265494 19265749 255 0
CTCF G2GSE9613 19267842 19268320 478 0
ER Breast-CancerGSE22609 19202443 19203119 676 0
ETS1 JurkatGSE17954 19191255 19192664 1409 0
FOXA1 MCF7GSE15244 19193137 19193643 506 0
H3K4me2 HCT116GSE10453 19193137 19194016 879 0
H3K4me3 colorectalcancer 19193137 19193509 372 0
H3ac HepG2E 19193137 19194305 1168 0
H3ac HepG2E 19195219 19195487 268 0
Oct4 hESGSE17917 19248693 19248930 237 0
P300 T30-glioblastomaGSE21026 19252805 19254118 1313 0
PHF8 293TGSE20725 19191321 19192493 1172 0
PHF8 HeLaGSE20725 19191440 19192611 1171 0
RARA MCF7GSE15244 19251131 19252098 967 0
RARA MCF7GSE15244 19252438 19252736 298 0
RARG MCF7GSE15244 19193137 19193509 372 0
RARG MCF7GSE15244 19251021 19252098 1077 0
Rb GrowingGSE19898 19214877 19215034 157 0
Rb GrowingGSE19898 19238735 19238972 237 0
Rb QuiescentGSE19898 19202277 19202399 122 0
Rb SenescentGSE19898 19199243 19199518 275 0
Rb shRbSenescenceGSE19898 19214965 19215334 369 0
STAT1 HeLaGSE12783 19247577 19249219 1642 0
STAT1 IFNSISSRdata 19248192 19249013 821 0
TAF k562GSE8489 19191814 19192653 839 0
TFAP2C MCF7GSE21234 19214650 19216077 1427 0
TFAP2C MCF7GSE21234 19251436 19252166 730 0
hScc1 BcellGSE12603 19236531 19236904 373 0
hScc1 BcellGSE12603 19248477 19249026 549 0
hScc1 BcellGSE12603 19250629 19251131 502 0
hScc1 BcellGSE12603 19266767 19267246 479 0
hScc1 CdLSGSE12603 19248549 19249026 477 0
p130 SenescentGSE19898 19253741 19253911 170 0
p130 shRbQuiescentGSE19898 19199066 19199720 654 0
p130 shRbQuiescentGSE19898 19215593 19216108 515 0
p130 shRbQuiescentGSE19898 19253700 19254098 398 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
17171 mRNA PCQAP chr22 19186439 19266472 1801 EST chr22 19200910 19202711 Non-exonic Bidirectional (NOB) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved