AutismKB 2.0

Annotation Detail for PIAS4


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Basic Information Top
Gene Symbol:PIAS4 ( FLJ12419,MGC35296,PIASY,Piasg,ZMIZ6 )
Gene Full Name: protein inhibitor of activated STAT, 4
Band: 19p13.3
Quick LinksEntrez ID:51588; OMIM: 605989; Uniprot ID:PIAS4_HUMAN; ENSEMBL ID: ENSG00000105229; HGNC ID: 17002
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
2N-acetylalanine.
24LXXLL motif.
114N6-acetyllysine.
125N6-acetyllysine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
51Phosphoserine(ATM)HMM predict
99Phosphothreonine(MAPK)HMM predict
217N-linkedHMM predict
244N-linkedHMM predict
280Phosphothreonine(CK2)HMM predict
280Phosphothreonine(PKC)HMM predict
416Phosphoserine(CDK)HMM predict
439N-linkedHMM predict
474Phosphoserine(CK1)HMM predict
474Phosphoserine(CK2)HMM predict
475Phosphoserine(CK1)HMM predict
476Phosphoserine(CK2)HMM predict
500CysteineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_015897
  • Location:chr19 3958748-3989064
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 3958263 3958548 285 343
CTCF CD4SISSRdata 3958263 3958548 285 343
ETS1 JurkatGSE17954 3958004 3959201 1197 146
NFkBII GM15510GSE19485 3958016 3959148 1132 167
Nanog ESGSE20650 3950074 3950372 298 8526
Oct1 HelaGSE14283 3954806 3954837 31 3927
PHF8 293TGSE20725 3957993 3959091 1098 207
PHF8 HeLaGSE20725 3958014 3959256 1242 114
TFAP2C MCF7GSE21234 3958209 3958642 433 323
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 3976576 3976754 178 0
H3ac HepG2E 3959470 3960655 1185 0
USF1 HepG2E 3959521 3960735 1214 0
USF2 HepG2E 3959784 3960477 693 0
hScc1 BcellGSE12603 3964052 3964492 440 0
hScc1 BcellGSE12603 3965435 3965967 532 0
hScc1 BcellGSE12603 3966747 3967052 305 0
hScc1 BcellGSE12603 3974957 3975320 363 0
hScc1 BcellGSE12603 3979080 3980030 950 0
hScc1 BcellGSE12603 3981968 3982393 425 0
hScc1 BcellGSE12603 3984557 3985016 459 0
p130 SenescentGSE19898 3987564 3988051 487 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018