AutismKB 2.0

Annotation Detail for LUC7L2


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Basic Information Top
Gene Symbol:LUC7L2 ( CGI-74,FLJ10657,LUC7B2,hLuc7B2 )
Gene Full Name: LUC7-like 2 (S. cerevisiae)
Band: 7q34
Quick LinksEntrez ID:51631; OMIM: 613056; Uniprot ID:LC7L2_HUMAN; ENSEMBL ID: ENSG00000146963; HGNC ID: 21608
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
17Phosphothreonine.
18Phosphoserine.
111Phosphothreonine.
122N6-acetyllysine.
2665-hydroxylysine; by JMJD6.
2695-hydroxylysine; by JMJD6.
354Phosphoserine.
358Phosphoserine.
383Phosphoserine.
384Phosphoserine.
Location(AA) Modifications Resource
354PhosphoserinePhospho.ELM 6.0
358Phosphoserine.Swiss-Prot 53.0
358PhosphoserinePhospho.ELM 6.0
383Phosphoserine (By similarity).Swiss-Prot 53.0
384Phosphoserine (By similarity).Swiss-Prot 53.0
Location(AA) Modification Resource
101Phosphothreonine(PKA)HMM predict
152Phosphoserine(ATM)HMM predict
265Phosphoserine(IKK)HMM predict
283Phosphoserine(PKB)HMM predict
292Phosphothreonine(PKC)HMM predict
292Phosphothreonine(PKA)HMM predict
294Phosphoserine(CAMK2)HMM predict
307Phosphoserine(CK1)HMM predict
313Phosphoserine(CK1)HMM predict
331Phosphoserine(CK1)HMM predict
336Phosphoserine(PKG)HMM predict
336Phosphoserine(PKA)HMM predict
336Phosphoserine(PKA)HMM predict
371Phosphotyrosine(EGFR)HMM predict
383PhosphoserineHMM predict
383Phosphoserine(CK1)HMM predict
383Phosphoserine(CK2)HMM predict
384Phosphoserine(CK2)HMM predict
384Phosphoserine(CK1)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_016019
  • Location:chr7 138695173-138758737
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 138694668 138695665 997 7
ETS1 JurkatGSE17954 138694304 138695403 1099 320
Oct1 HelaGSE14283 138694815 138694849 34 342
PHF8 HeLaGSE20725 138693688 138695982 2294 339
PHF8 Hs68plusFBSGSE20725 138693937 138696365 2428 23
Pol2 GM12878GSE19551 138693914 138696132 2218 151
TAF HelaGSE8489 138693630 138693956 326 1381
TAF k562GSE8489 138694311 138694955 644 541
TFAP2C MCF7GSE21234 138694761 138695421 660 83
hScc1 BcellGSE12603 138694496 138695561 1065 145
p130 QuiescentGSE19898 138694624 138695375 751 174
p130 SenescentGSE19898 138694404 138695281 877 331
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 138769868 138770114 246 11254
CTCF CD4SISSRdata 138769868 138770114 246 11254
CTCF G2GSE9613 138769585 138769964 379 11037
Myc K562GSE19551 138769818 138770220 402 11282
Oct1 HelaGSE14283 138772285 138772334 49 13572
Pol2 GM12878GSE19551 138762389 138763033 644 3974
TFAP2C MCF7GSE21234 138766198 138766807 609 7765
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ER Fulvestrant-MCF7GSE14664 138703047 138703081 34 0
ER Fulvestrant-MCF7GSE14664 138726708 138726742 34 0
FOXA1 MCF7GSE15244 138695665 138696345 680 0
Fos K562GSE19551 138694399 138696146 1747 0
H3K4me3 colorectalcancer 138696088 138696517 429 0
H3ac HepG2E 138695833 138697270 1437 0
NFkBII GM15510GSE19485 138694171 138696422 2251 0
Nanog hESGSE18292 138705322 138705636 314 0
Oct1 H2O2-HelaGSE14283 138756273 138756305 32 0
Oct1 H2O2-HelaGSE14283 138756425 138756452 27 0
Oct1 HelaGSE14283 138702543 138702579 36 0
Oct1 HelaGSE14283 138712894 138712933 39 0
Oct1 HelaGSE14283 138739254 138739314 60 0
Oct1 HelaGSE14283 138747441 138747475 34 0
Oct1 HelaGSE14283 138749969 138750009 40 0
Oct1 HelaGSE14283 138756274 138756345 71 0
RNAII Tamoxifen-MCF7GSE14664 138739273 138739313 40 0
Rb GrowingGSE19898 138695680 138696108 428 0
Rb QuiescentGSE19898 138695635 138696203 568 0
Rb SenescentGSE19898 138694655 138696044 1389 0
Rb shRbSenescenceGSE19898 138695638 138695925 287 0
TAF HelaGSE8489 138695927 138697270 1343 0
TAF k562GSE8489 138695833 138697407 1574 0
TFAP2C MCF7GSE21234 138695539 138696230 691 0
p130 QuiescentGSE19898 138695434 138696010 576 0
p130 SenescentGSE19898 138695394 138696335 941 0
p130 shRbQuiescentGSE19898 138694811 138695537 726 0
p130 shRbQuiescentGSE19898 138695636 138696238 602 0
p130 shRbSenescentGSE19898 138694469 138696290 1821 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-1 hsa-mir-1-2 18 15685193
hsa-miR-1 hsa-mir-1-1 20 15685193
hsa-miR-124 hsa-mir-124-1 8 15685193
hsa-miR-124 hsa-mir-124-2 8 15685193
hsa-miR-124 hsa-mir-124-3 20 15685193
hsa-miR-373 hsa-mir-373 19 15685193
hsa-miR-373* hsa-mir-373 19 15685193
ID in Tarbase Data Type Support Type miRNA Gene Direct Support Publication
632 Unknown MicroArray miR-373 LUC7L2 n_a 15685193
Ensembl Protein Type Differentially expressed in Pathology or Event Mis Regulation Gene Expression Tumour Involvement
ENSG00000146963 n_a n_a n_a "lymphoblast, lymphocyte, muscle cell" "benign tumour, malignant tumour, carcinoma, leukaemia, sarcoma"
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
24712 mRNA LUC7L2 chr7 138502262 138565453 259 EST chr7 138559456 138569527Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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