AutismKB 2.0

Annotation Detail for PDK4


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Basic Information Top
Gene Symbol:PDK4 ( FLJ40832 )
Gene Full Name: pyruvate dehydrogenase kinase, isozyme 4
Band: 7q21.3
Quick LinksEntrez ID:5166; OMIM: 602527; Uniprot ID:PDK4_HUMAN; ENSEMBL ID: ENSG00000004799; HGNC ID: 8812
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
127Phosphohistidine; by autocatalysis (By
Location(AA) Modifications Resource
127Phosphohistidine (by autocatalysis) (Bysimilarity).Swiss-Prot 53.0
Location(AA) Modification Resource
33Phosphoserine(CDC2)HMM predict
33Phosphoserine(ATM)HMM predict
81N-linkedHMM predict
187N-linkedHMM predict
274Phosphothreonine(MAPK)HMM predict
310O-linkedHMM predict
368Phosphoserine(CK1)HMM predict
368Phosphoserine(CK2)HMM predict
379N-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_002612
  • Location:chr7 95050748-95063860
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
FoxA1 MCF7MACSdata 95076002 95076319 317 12300
P300 T30-glioblastomaGSE21026 95075528 95077641 2113 12724
RNAII Tamoxifen-MCF7GSE14664 95069570 95069668 98 5759
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
TFAP2C MCF7GSE21234 95044416 95044792 376 6145
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3K4me3 colorectalcancer 95062646 95063524 878 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-1 hsa-mir-1-2 18 19440340
hsa-miR-1 hsa-mir-1-1 20 19440340
hsa-miR-107 hsa-mir-107 10 19440340
hsa-miR-133a hsa-mir-133a-1 18 19440340
hsa-miR-133a hsa-mir-133a-2 20 19440340
hsa-miR-133b hsa-mir-133b 6 19440340
hsa-miR-181a hsa-mir-181a-2 9 19440340
hsa-miR-181a hsa-mir-181a-1 1 19440340
hsa-miR-181a* hsa-mir-181a-1 1 19440340
hsa-miR-181a-2* hsa-mir-181a-2 9 19440340
hsa-miR-181b hsa-mir-181b-1 1 19440340
hsa-miR-181b hsa-mir-181b-2 9 19440340
hsa-miR-181c hsa-mir-181c 19 19440340
hsa-miR-181c* hsa-mir-181c 19 19440340
hsa-miR-181d hsa-mir-181d 19 19440340
hsa-miR-23a hsa-mir-23a 19 19440340
hsa-miR-23a* hsa-mir-23a 19 19440340
hsa-miR-23b hsa-mir-23b 9 19440340
hsa-miR-23b* hsa-mir-23b 9 19440340
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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