AutismKB 2.0

Annotation Detail for CPSF3


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Basic Information Top
Gene Symbol:CPSF3 ( CPSF,CPSF-73,CPSF73,YSH1 )
Gene Full Name: cleavage and polyadenylation specific factor 3, 73kDa
Band: 2p25.1
Quick LinksEntrez ID:51692; OMIM: 606029; Uniprot ID:CPSF3_HUMAN; ENSEMBL ID: ENSG00000119203; HGNC ID: 2326
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
681Phosphothreonine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
343Phosphoserine(IKK)HMM predict
399Phosphotyrosine(Syk)HMM predict
399SulfotyrosineHMM predict
402Phosphothreonine(PKC)HMM predict
502N-linkedHMM predict
503Phosphotyrosine(INSR)HMM predict
553N-linkedHMM predict
576Phosphotyrosine(Jak)HMM predict
659Phosphoserine(CK2)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_016207
  • Location:chr2 9481318-9530677
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
p130 shRbSenescentGSE19898 9480961 9481547 586 65
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 9484941 9485228 287 0
CTCF G2GSE9613 9492218 9492416 198 0
CTCF G2GSE9613 9525417 9525557 140 0
ER E2-MCF7GSE14664 9520610 9520642 32 0
ER Fulvestrant-MCF7GSE14664 9495540 9495629 89 0
ER Fulvestrant-MCF7GSE14664 9511978 9512021 43 0
GABP k562GSE8489 9481223 9483199 1976 0
GABP k562GSE8489 9483641 9485264 1623 0
H3K4me2 HCT116GSE10453 9482078 9483235 1157 0
H3K4me3 colorectalcancer 9481599 9482290 691 0
H3ac HepG2E 9481373 9483267 1894 0
Oct1 H2O2-HelaGSE14283 9511289 9511315 26 0
Oct1 HelaGSE14283 9511289 9511332 43 0
Oct1 HelaGSE14283 9529622 9529664 42 0
RNAII Tamoxifen-MCF7GSE14664 9512782 9512839 57 0
TAF k562GSE8489 9481670 9482468 798 0
p130 shRbQuiescentGSE19898 9481661 9482106 445 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018