AutismKB 2.0

Annotation Detail for SERPINF1


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Basic Information Top
Gene Symbol:SERPINF1 ( EPC-1,PEDF )
Gene Full Name: serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
Band: 17p13.3
Quick LinksEntrez ID:5176; OMIM: 172860; Uniprot ID:PEDF_HUMAN; ENSEMBL ID: ENSG00000132386; HGNC ID: 8824
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
20Pyrrolidone carboxylic acid.
24Phosphoserine; by CK2.
114Phosphoserine; by CK2.
227Phosphoserine; by PKA.
285N-linked (GlcNAc...).
Location(AA) Modifications Resource
20Pyrrolidone carboxylic acid.Swiss-Prot 53.0
285N-linked (GlcNAc...).Swiss-Prot 53.0
Location(AA) Modification Resource
9S-palmitoylHMM predict
24Phosphoserine(ATM)HMM predict
24Phosphoserine(MAPK)HMM predict
24Phosphoserine(CDC2)HMM predict
30O-linkedHMM predict
71Phosphoserine(IKK)HMM predict
71Phosphoserine(PKA)HMM predict
73Phosphoserine(CDC2)HMM predict
73Phosphoserine(IKK)HMM predict
81Phosphoserine(CDC2)HMM predict
81Phosphoserine(MAPK)HMM predict
164Phosphothreonine(PKC)HMM predict
227Phosphoserine(PKG)HMM predict
232Phosphotyrosine(Jak)HMM predict
232Phosphotyrosine(Syk)HMM predict
285N-linkedHMM predict
313Phosphothreonine(PKC)HMM predict
328Phosphoserine(IKK)HMM predict
340Phosphoserine(CDC2)HMM predict
371Phosphothreonine(PKC)HMM predict
372Phosphothreonine(MAPK)HMM predict
372Phosphothreonine(CDC2)HMM predict
372O-linkedHMM predict
374O-linkedHMM predict
374Phosphoserine(MAPK)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_002615
  • Location:chr17 1612008-1627616
  • strand:+
No data
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 1611888 1612220 332 0
ER MCF7GSE19013 1626877 1627313 436 0
FOXA1 MCF7GSE15244 1619830 1620465 635 0
FoxA1 MCF7MACSdata 1620102 1620496 394 0
H3ac HepG2E 1611888 1613926 2038 0
Nanog hESGSE18292 1613295 1613448 153 0
PHF8 293TGSE20725 1611192 1612974 1782 0
RARA MCF7GSE15244 1619969 1620465 496 0
RARG MCF7GSE15244 1619934 1620465 531 0
RARG MCF7GSE15244 1620963 1621261 298 0
TFAP2C MCF7GSE21234 1619762 1620517 755 0
TFAP2C MCF7GSE21234 1626890 1627447 557 0
p130 QuiescentGSE19898 1614434 1614760 326 0
p130 SenescentGSE19898 1612916 1613590 674 0
p130 SenescentGSE19898 1614365 1614797 432 0
p130 shRbQuiescentGSE19898 1614196 1614954 758 0
p130 shRbSenescentGSE19898 1612994 1613319 325 0
p130 shRbSenescentGSE19898 1620258 1620438 180 0
p63 keratinocytesGSE17611 1619744 1620863 1119 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018