AutismKB 2.0

Annotation Detail for RAB8B


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Basic Information Top
Gene Symbol:RAB8B ( FLJ38125 )
Gene Full Name: RAB8B, member RAS oncogene family
Band: 15q22.2
Quick LinksEntrez ID:51762; OMIM: 613532; Uniprot ID:RAB8B_HUMAN; ENSEMBL ID: ENSG00000166128; HGNC ID: 30273
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
3N6-acetyllysine.
5Phosphotyrosine.
45Effector region (By similarity).
204Cysteine methyl ester (Potential).
Location(AA) Modifications Resource
204S-geranylgeranyl cysteine (Bysimilarity).Swiss-Prot 53.0
Location(AA) Modification Resource
34N-linkedHMM predict
36O-linkedHMM predict
132Phosphoserine(PKG)HMM predict
178N-linkedHMM predict
181N-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_016530
  • Location:chr15 61268780-61347023
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ETS1 JurkatGSE17954 61268079 61269012 933 235
Oct1 HelaGSE14283 61266719 61266758 39 2042
PHF8 293TGSE20725 61268156 61269403 1247 1
TFAP2C MCF7GSE21234 61265248 61265854 606 3230
hScc1 BcellGSE12603 61268367 61268955 588 120
p130 SenescentGSE19898 61268345 61268772 427 222
p130 shRbQuiescentGSE19898 61267977 61268655 678 465
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
KLF4 hESGSE17917 61349676 61349835 159 2732
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 61283070 61283246 176 0
CTCF CD4SISSRdata 61283070 61283246 176 0
FOXA1 eGFPGSE10845 61291392 61291793 401 0
H3K4me3 colorectalcancer 61269306 61269984 678 0
H3ac HepG2E 61269306 61270165 859 0
NRSF mAbJurkat 61269552 61270337 785 0
Oct1 H2O2-HelaGSE14283 61300614 61300643 29 0
Oct4 hESGSE17917 61335612 61335980 368 0
PAX3-FKHR Rh4GSE19063 61317559 61318757 1198 0
RARA MCF7GSE15244 61326592 61326955 363 0
hScc1 BcellGSE12603 61329981 61330123 142 0
p63 keratinocytesGSE17611 61302730 61303350 620 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018