AutismKB 2.0

Annotation Detail for ZAK


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:ZAK ( AZK,MLK7,MLT,MLTK,MRK,mlklak,pk )
Gene Full Name: -
Band: 2q24.2
Quick LinksEntrez ID:51776; OMIM: 609479; Uniprot ID:MLTK_HUMAN; ENSEMBL ID: ENSG00000091436; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
2Phosphoserine.
3Phosphoserine.
155Phosphoserine.
161Phosphothreonine; by autocatalysis.
165Phosphoserine; by autocatalysis.
264Phosphoserine.
268Phosphoserine.
275Phosphoserine.
302Phosphoserine.
326Phosphoserine.
328Phosphothreonine.
557Phosphoserine.
565Phosphoserine.
568Phosphoserine.
584Phosphoserine.
586Phosphothreonine.
591Phosphoserine.
593Phosphoserine.
599Phosphoserine.
628Phosphothreonine.
633Phosphoserine.
635Phosphoserine.
636Phosphoserine.
637Phosphoserine.
639Phosphothreonine.
648Phosphoserine.
660Phosphoserine.
666Phosphothreonine.
667Phosphoserine.
668Phosphoserine.
687Phosphoserine.
690Phosphoserine.
691Phosphoserine.
718Phosphoserine.
727Phosphoserine.
733Phosphoserine.
754Phosphoserine.
781Phosphoserine.
Location(AA) Modifications Resource
161Phosphothreonine (by autocatalysis).Swiss-Prot 53.0
161PhosphothreoninePhospho.ELM 6.0
162PhosphothreoninePhospho.ELM 6.0
165Phosphoserine (by autocatalysis).Swiss-Prot 53.0
165PhosphoserinePhospho.ELM 6.0
635Phosphoserine (By similarity).Swiss-Prot 53.0
637Phosphoserine.Swiss-Prot 53.0
639Phosphothreonine (By similarity).Swiss-Prot 53.0
Location(AA) Modification Resource
58Phosphoserine(CK1)HMM predict
78Phosphotyrosine(Abl)HMM predict
78Phosphotyrosine(SRC)HMM predict
93Phosphotyrosine(INSR)HMM predict
120Phosphotyrosine(Jak)HMM predict
159N-linkedHMM predict
226Phosphothreonine(PKC)HMM predict
252Phosphoserine(PKC)HMM predict
265N-linkedHMM predict
372N-linkedHMM predict
460Phosphotyrosine(INSR)HMM predict
509Phosphothreonine(PKC)HMM predict
522Phosphothreonine(MAPK)HMM predict
522Phosphothreonine(CDK)HMM predict
522Phosphothreonine(CDC2)HMM predict
567Phosphoserine(IKK)HMM predict
585N-linkedHMM predict
591Phosphoserine(IKK)HMM predict
591Phosphoserine(ATM)HMM predict
593Phosphoserine(PKA)HMM predict
599Phosphoserine(CDC2)HMM predict
631N-linkedHMM predict
635Phosphoserine(CDC2)HMM predict
635O-linkedHMM predict
636Phosphoserine(CK1)HMM predict
637Phosphoserine(IKK)HMM predict
641Phosphotyrosine(SRC)HMM predict
646N-linkedHMM predict
666Phosphothreonine(CK2)HMM predict
689N-linkedHMM predict
691Phosphoserine(CDK)HMM predict
691Phosphoserine(CDC2)HMM predict
697Phosphoserine(PKG)HMM predict
700PhosphoserineHMM predict
703Phosphoserine(IKK)HMM predict
704Phosphothreonine(CDK)HMM predict
704Phosphothreonine(CDC2)HMM predict
704Phosphothreonine(MAPK)HMM predict
707MethylarginineHMM predict
720Phosphoserine(IKK)HMM predict
757Phosphoserine(CK1)HMM predict
761Phosphoserine(CK1)HMM predict
781Phosphoserine(CDC2)HMM predict
785Phosphothreonine(PKC)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_016653
  • Location:chr2 173648810-173840981
  • strand:+
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 173844401 173844730 329 3584
Oct1 HelaGSE14283 173848695 173848728 33 7730
Oct1 HelaGSE14283 173860843 173860876 33 19878
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ER Fulvestrant-MCF7GSE14664 173827774 173827807 33 0
Myc hESGSE17917 173825862 173826231 369 0
Nanog hESGSE18292 173809474 173809853 379 0
Nanog hESGSE18292 173831670 173832045 375 0
Oct1 H2O2-HelaGSE14283 173827780 173827813 33 0
Oct1 HelaGSE14283 173827774 173827810 36 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
15286 mRNA ZAK chr2 173766193 173958245 194 mRNA LOC339751 chr2 173887949 173972271Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved